ArticleApplied clinical informatics2024
Effects of a Pharmacist-Designed Clinical Decision Support System on Antimicrobial Stewardship.
Article in Applied clinical informatics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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Who cites it
3 citing papers in PubMed.
- A bibliometric analysis of the application trends of information technology in antimicrobial stewardship within hospitals.European journal of hospital pharmacy : science and practice · 2026Article
- Optimizing antimicrobial stewardship in urology: a qualitative study on needs, values and requirements for clinical decision support.Infection prevention in practice · 2026Article
- Optimization of Postoperative Antimicrobial Therapy in Surgical Patients Using a Clinical Decision Support System: Use Patterns and Clinical Outcomes.Medicina (Kaunas, Lithuania) · 2025Article
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundClinical decision support systems (CDSSs) are computer applications, which can be applied to give guidance to practitioners in antimicrobial stewardship (AS) activities; however, further information is needed for their optimal use.
objectivesOur objective was to analyze the implementation of a CDSS program in a second-level hospital, describing alerts, recommendations, and the effects on consumption and clinical outcomes.
methodsIn October 2020, a pharmacist-driven CDSS designed for AS was implemented in a second-level hospital. The program provides a list of alerts related to antimicrobial treatment and microbiology, which were automatized for revision by the AS professionals. To analyze the implementation of the CDSS, a pre-post-intervention, retrospective study was designed. AS-triggered alerts and recommendations (total number and rate of acceptance) were compiled. The effect of the CDSS was measured using antimicrobial consumption, duration of antimicrobial treatments, in-hospital mortality, and length of stay (LOS) for patients admitted for infectious causes.
resultsThe AS team revised a total of 7,543 alerts and 772 patients had at least one recommendation, with an acceptance rate of 79.3%. Antimicrobial consumption decreased from 691.1 to 656.8 defined daily doses (DDD)/1,000 beds-month (
conclusionThe implementation of a CDSS resulted in a significant reduction of antimicrobial DDD, duration of antimicrobial treatments, and hospital LOS. There was no significant difference in mortality.
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