Evidence map›Paper›PMID 38857399›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2024

Inhibition of a cyclic nucleotide-gated channel on neuronal cilia activates unfolded protein response in intestinal cells to promote longevity.

Dongdong Li, Di Chen, Wei Li, Guangshuo Ou

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Dongdong LiTsinghua-Peking Center for Life Sciences, Tsinghua University, Beijing, China.ORCID 0000-0003-2515-1115
Di ChenZhejiang University-University of Edinburgh Institute, Zhejiang University School of Medicine, Hangzhou, China.
Wei LiSchool of Medicine, Tsinghua University, Beijing, China.ORCID 0000-0001-9133-461X
Guangshuo OuTsinghua-Peking Center for Life Sciences, Tsinghua University, Beijing, China.ORCID 0000-0003-1512-7824

Funding

China Postdoctoral Science Foundation (China Postdoctoral Foundation Project) 2022M711844National Natural Science Foundation of China 31991191National Natural Science Foundation of China 32100538Young Elite Scientists Sponsorship Program by CAST YESS20220102
6 · The paper itself

Abstract

Ciliary defects are linked to ciliopathies, but impairments in the sensory cilia of

Indexed as

Caenorhabditis elegansCaenorhabditis elegans ProteinsCiliaLongevityUnfolded Protein ResponseAnimalsCyclic Nucleotide-Gated Cation ChannelsEndoplasmic ReticulumInsulin-Like Growth Factor IIntestinal MucosaIntestinesNeuronsSignal TransductionCaenorhabditis elegans ProteinsCyclic Nucleotide-Gated Cation ChannelsInsulin-Like Growth Factor ICNG channellifespanneuronal ciliaUPRER

Identifiers

PMID38857399
PMCPMC11194586

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.