Evidence map›Paper›PMID 38857064›Full record

ArticleeLife2024

Secreted antigen A peptidoglycan hydrolase is essential for

Steven Klupt, Kyong Tkhe Fam, Xing Zhang, Pavan Kumar Chodisetti, Abeera Mehmood, Tumara Boyd, Danielle Grotjahn, Donghyun Park, Howard C Hang

Abstract read
In one paragraph

Article in eLife, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Review
  9. Frontiers in immunology · 2026
    Review
  10. Article
  11. Journal of bacteriology · 2025
    Article
  12. Review
  13. Review
  14. The SagA ofeLife · 2024
    Article
  15. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors.

Steven Klupt *Department of Immunology and Microbiology, Scripps Research, La Jolla, United States.
Kyong Tkhe Fam *Department of Immunology and Microbiology, Scripps Research, La Jolla, United States.ORCID https://orcid.org/0000-0002-4877-5679
Xing Zhang *Department of Immunology and Microbiology, Scripps Research, La Jolla, United States.
Pavan Kumar ChodisettiDepartment of Immunology and Microbiology, Scripps Research, La Jolla, United States.
Abeera MehmoodDepartment of Immunology and Microbiology, Scripps Research, La Jolla, United States.
Tumara BoydDepartment of Integrative Structural & Computational Biology, Scripps Research, La Jolla, United States.
Danielle GrotjahnDepartment of Integrative Structural & Computational Biology, Scripps Research, La Jolla, United States.
Donghyun ParkDepartment of Integrative Structural & Computational Biology, Scripps Research, La Jolla, United States.
Howard C HangDepartment of Immunology and Microbiology, Scripps Research, La Jolla, United States.ORCID https://orcid.org/0000-0003-4053-5547

Funding

Translation of commensal bacteria mechanism for immunotherapyR01CA245292 · NCI · SCRIPPS RESEARCH INSTITUTE, THE · PI HANG, HOWARD C · 2020 to 2024
$2.7M
High-speed direct detector for cryo electron microscopyS10OD032467 · OD · SCRIPPS RESEARCH INSTITUTE, THE · PI LANDER, GABRIEL C · 2022 to 2022
$600k
NCI NIH HHS R01 CA245292NIH HHS CA245292NIH HHS S10 OD032467Scripps Research Institute David C. Fairchild Endowed FellowshipScripps Research Institute Start-up funds
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Bacterial ProteinsEnterococcus faeciumImmune Checkpoint InhibitorsN-Acetylmuramoyl-L-alanine AmidaseAnimalsHumansMicePeptidoglycanBacterial ProteinsImmune Checkpoint InhibitorsN-Acetylmuramoyl-L-alanine AmidasePeptidoglycancancer immunotherapyEnterococcus faeciumimmunologyinflammationmouseNOD2

Identifiers

PMID38857064
PMCPMC11164530

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.