Evidence map›Paper›PMID 38856952›Full record

ArticleDrug delivery and translational research2024

Understanding the role of the structure of single-stimuli hybrid systems on their behaviour as platforms for colonic delivery.

Joaquín González-Fuentes, María Plaza-Oliver, Manuel Jesús Santander-Ortega, María Victoria Lozano

Abstract read
PubMed Publisher
In one paragraph

Article in Drug delivery and translational research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Joaquín González-FuentesDevelopment and Evaluation of Nanomedicines (DEVANA), Faculty of Pharmacy, Albacete, Spain.
María Plaza-OliverDevelopment and Evaluation of Nanomedicines (DEVANA), Faculty of Pharmacy, Albacete, Spain.
Manuel Jesús Santander-OrtegaDevelopment and Evaluation of Nanomedicines (DEVANA), Faculty of Pharmacy, Albacete, Spain. manuel.santander@uclm.es.
María Victoria LozanoDevelopment and Evaluation of Nanomedicines (DEVANA), Faculty of Pharmacy, Albacete, Spain. mvictoria.lozano@uclm.es.ORCID 0000-0001-7774-732X

Funding

European Regional Development Fund SBPLY/21/180501/000077Junta de Comunidades de Castilla-La Mancha SBPLY/21/180501/000077Ministerio de Universidades NextGenerationEU UNI/551/2021Universidad de Castilla-La Mancha NextGenerationEU UNI/551/2021
6 · The paper itself

Abstract

The success of colon-targeted oral hybrid systems relies in the proper control over the release of the entrapped nanostructures at the colon. This work describes the design of hybrid systems for their colonic enzyme-triggered release. The hybrid systems were constituted by nanoemulsions, with adequate characteristics for the treatment of ulcerative colitis, included in a pectin hydrogel-like matrix. For that purpose, pectins with similar degrees of methylation (< 50%) and increasing degree of amidation, i.e. 0, 13 and 20%, were selected. Hybrid systems were formulated by a novel aggregation induced gelation method, using Ca

Indexed as

ColonPectinsDrug Delivery SystemsEmulsionsHumansHydrogelsEmulsionsHydrogelsPectinsColon-targeted oral drug deliveryHybrid systemNanoemulsionParticle trackingPectin

Identifiers

PMID38856952

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.