Influence of framing coil orientation and its shape on the hemodynamics of a basilar aneurysm model.

Nisanth Kumar Panneerselvam, B J Sudhir, Santhosh K Kannath, B S V Patnaik

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Article in Medical & biological engineering & computing, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

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4 authors.

Nisanth Kumar PanneerselvamDepartment of Applied Mechanics and Biomedical Engineering, Indian Institute of Technology Madras, Chennai, 600036, Tamilnadu, India.

B J SudhirDepartment of Neurosurgery, Sree Chitra Tirunal Institute for Medical Sciences and Technology, Thiruvananthapuram, 695011, Kerala, India. bjs@sctimst.ac.in.

Santhosh K KannathDepartment of Imaging Sciences and Interventional Radiology, Sree Chitra Tirunal Institute for Medical Sciences and Technology, Thiruvananthapuram, 695011, Kerala, India.

B S V PatnaikDepartment of Applied Mechanics and Biomedical Engineering, Indian Institute of Technology Madras, Chennai, 600036, Tamilnadu, India. bsvp@iitm.ac.in.ORCID http://orcid.org/0000-0002-4752-2602

Funding

National supercomputing mission (NSM), Government of India SP/2021/008273Scientific and useful profound Research (SERB-SUPRA), Government of India SPR/2020/000298

6 · The paper itself

Abstract

Aneurysms are bulges of an artery, which require clinical management solutions. Due to the inherent advantages, endovascular coil filling is emerging as the treatment of choice for intracranial aneurysms (IAs). However, after successful treatment of coil embolization, there is a serious risk of recurrence. It is well known that optimal packing density will enhance treatment outcomes. The main objective of endovascular coil embolization is to achieve flow stasis by enabling significant reduction in intra-aneurysmal flow and facilitate thrombus formation. The present study numerically investigates the effect of framing coil orientation on intra-aneurysmal hemodynamics. For the purpose of analysis, actual shape of the embolic coil is used, instead of simplified ideal coil shape. Typically used details of the framing coil are resolved for the analysis. However, region above the framing coil is assumed to be filled with a porous medium. Present simulations have shown that orientation of the framing coil loop (FCL) greatly influences the intra-aneurysmal hemodynamics. The FCLs which were placed parallel to the outlets of basilar tip aneurysm (Coil A) were found to reduce intra-aneurysmal flow velocity that facilitates thrombus formation. Involving the coil for the region is modeled using a porous medium model with a packing density of 20

Indexed as

Embolization, TherapeuticHemodynamicsIntracranial AneurysmBasilar ArteryComputer SimulationHumansModels, CardiovascularCardiovascular diseaseCoil embolizationComputational fluid dynamicsHemodynamicsIntracranial aneurysm

Identifiers

PMID38856881

DOI10.1007/s11517-024-03146-4

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.