Evidence map›Paper›PMID 38856832›Full record

ArticleCell biochemistry and biophysics2024

ClinOleic Impairs ROS Production and Phagocytosis in M1 Macrophages Without Affecting M1 Differentiation.

Yi-Sheng Tsai, Hsuan-Te Yeh, Ming-Shan Chen, Hui-Ju Chang, Wen-Chun Lin, Shew-Meei Sheu

Abstract read
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In one paragraph

Article in Cell biochemistry and biophysics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. The Herbal PairFood science & nutrition · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Yi-Sheng TsaiDepartment of Anesthesiology, Ditmanson Medical Foundation Chia-Yi Christian Hospital, 60002, Chia-Yi City, Taiwan.
Hsuan-Te YehDepartment of Anesthesiology, Ditmanson Medical Foundation Chia-Yi Christian Hospital, 60002, Chia-Yi City, Taiwan.
Ming-Shan ChenDepartment of Anesthesiology, Ditmanson Medical Foundation Chia-Yi Christian Hospital, 60002, Chia-Yi City, Taiwan.
Hui-Ju ChangDepartment of Medical Research, Ditmanson Medical Foundation Chia-Yi Christian Hospital, 60002, Chia-Yi City, Taiwan.
Wen-Chun LinDepartment of Medical Research, Ditmanson Medical Foundation Chia-Yi Christian Hospital, 60002, Chia-Yi City, Taiwan.
Shew-Meei SheuDepartment of Medical Research, Ditmanson Medical Foundation Chia-Yi Christian Hospital, 60002, Chia-Yi City, Taiwan. cych12554@gmail.com.

Funding

Ditmanson Medical Foundation Chia-Yi Christian Hospital R110-32
6 · The paper itself

Abstract

Lipid emulsions are the primary source of calories and fatty acids that are used to provide essential energy and nutrients to patients suffering from severe intestinal failure and critical illness. However, their use has been linked to adverse effects on patient outcomes, notably affecting immune defenses and inflammatory responses. ClinOleic is a lipid emulsion containing a mixture of olive oil and soybean oil (80:20). The effect of ClinOleic on the differentiation of M1 macrophages remains unclear. In this study, we isolated human monocytes and added ClinOleic to differentiation culture media to investigate whether it affects monocyte polarization into M1 macrophages and macrophage functions, such as reactive oxygen species (ROS) production and phagocytosis. ROS production was stimulated by live S. aureus and detected with L-012, a chemiluminescence emission agent. Phagocytic capacity was assayed using pHrodo™ Green S. aureus Bioparticles

Indexed as

Cell DifferentiationMacrophagesPhagocytosisReactive Oxygen SpeciesStaphylococcus aureusCells, CulturedHumansInterleukin-6MonocytesOlive OilTumor Necrosis Factor-alphaInterleukin-6Olive OilReactive Oxygen SpeciesTumor Necrosis Factor-alphaClinOleicDifferentiationM1 macrophagesPhagocytosisROS

Identifiers

PMID38856832

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.