Evidence map›Paper›PMID 38856220›Full record

ArticleJournal of bacteriology2024

Identification of a copper-responsive small molecule inhibitor of uropathogenic

Braden S Hanson, Amanuel Hailemariam, Yongjian Yang, Faras Mohamed, George L Donati, Dwight Baker, James Sacchettini, James J Cai, Sargurunathan Subashchandrabose

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of bacteriology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. n-Butanol Extract ofCurrent issues in molecular biology · 2026
    Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Braden S HansonDepartment of Veterinary Pathobiology, College of Veterinary Medicine and Biomedical Sciences, Texas A&M University, College Station, Texas, USA.ORCID 0000-0001-9256-4708
Amanuel HailemariamDepartment of Biochemistry and Biophysics, College of Agriculture and Life Sciences, Texas A&M University, College Station, Texas, USA.
Yongjian YangDepartment of Veterinary Integrative Biosciences, College of Veterinary Medicine and Biomedical Sciences, Texas A&M University, College Station, Texas, USA.
Faras MohamedDepartment of Veterinary Pathobiology, College of Veterinary Medicine and Biomedical Sciences, Texas A&M University, College Station, Texas, USA.
George L DonatiDepartment of Chemistry, Wake Forest University, Winston-Salem, North Carolina, USA.
Dwight BakerDepartment of Biochemistry and Biophysics, College of Agriculture and Life Sciences, Texas A&M University, College Station, Texas, USA.
James SacchettiniDepartment of Biochemistry and Biophysics, College of Agriculture and Life Sciences, Texas A&M University, College Station, Texas, USA.
James J CaiDepartment of Veterinary Integrative Biosciences, College of Veterinary Medicine and Biomedical Sciences, Texas A&M University, College Station, Texas, USA.
Sargurunathan SubashchandraboseDepartment of Veterinary Pathobiology, College of Veterinary Medicine and Biomedical Sciences, Texas A&M University, College Station, Texas, USA.ORCID 0000-0003-1217-9813

Funding

Copper is a Host Effector in Protection Against Urinary Tract InfectionR01DK114224 · NIDDK · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI SUBASHCHANDRABOSE, SARGURUNATHAN · 2018 to 2022
$1.7M
Elucidating the Nexus Between Urinary Tract Infection and DiabetesR21AI166162 · NIAID · TEXAS A&M AGRILIFE RESEARCH · PI SUBASHCHANDRABOSE, SARGURUNATHAN · 2022 to 2023
$417k
HHS | NIH | National Institute of Allergy and Infectious Diseases (NIAID)HHS | NIH | National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)National Science Foundation (NSF)NIAID NIH HHS R21 AI166162NIDDK NIH HHS R01 DK114224
6 · The paper itself

Abstract

Urinary tract infections (UTIs) are a major global health problem and are caused predominantly by uropathogenic

Indexed as

Anti-Bacterial AgentsCopperMicrobial Sensitivity TestsUrinary Tract InfectionsUropathogenic Escherichia coliAcinetobacter baumanniiEscherichia coli InfectionsEscherichia coli ProteinsGene Expression Regulation, BacterialMethicillin-Resistant Staphylococcus aureusPseudomonas aeruginosaSmall Molecule LibrariesAnti-Bacterial AgentsCopperEscherichia coli ProteinsSmall Molecule LibrariesantimicrobialcopperE. coliisothiazoloneUPEC

Identifiers

PMID38856220
PMCPMC11270900

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.