Evidence map›Paper›PMID 38855666›Full record

ArticleBiomedical optics express2024

Tunable liquid lens for three-photon excitation microscopy.

Samuel D Gilinsky, Diane N Jung, Greg L Futia, Mo Zohrabi, Tarah A Welton, Omkar D Supekar, Emily A Gibson, Diego Restrepo, Victor M Bright, Juliet T Gopinath

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biomedical optics express, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Samuel D GilinskyDepartment of Electrical, Computer, and Energy Engineering, University of Colorado Boulder, Boulder, Colorado 80309, USA.
Diane N JungDepartment of Mechanical Engineering, University of Colorado Boulder, Boulder, Colorado 80309, USA.ORCID https://orcid.org/0009-0004-8500-4162
Greg L FutiaDepartment of Bioengineering, University of Colorado Anschutz Medical Campus, Aurora, Colorado 80045, USA.ORCID https://orcid.org/0000-0003-2266-9525
Mo ZohrabiDepartment of Electrical, Computer, and Energy Engineering, University of Colorado Boulder, Boulder, Colorado 80309, USA.
Tarah A WeltonDepartment of Bioengineering, University of Colorado Anschutz Medical Campus, Aurora, Colorado 80045, USA.
Omkar D SupekarDepartment of Electrical, Computer, and Energy Engineering, University of Colorado Boulder, Boulder, Colorado 80309, USA.ORCID https://orcid.org/0000-0003-1777-8508
Emily A GibsonDepartment of Bioengineering, University of Colorado Anschutz Medical Campus, Aurora, Colorado 80045, USA.
Diego RestrepoDepartment of Cell and Developmental Biology, University of Colorado Anschutz Medical Campus, Aurora, Colorado 80045, USA.
Victor M BrightDepartment of Mechanical Engineering, University of Colorado Boulder, Boulder, Colorado 80309, USA.
Juliet T GopinathDepartment of Electrical, Computer, and Energy Engineering, University of Colorado Boulder, Boulder, Colorado 80309, USA.ORCID https://orcid.org/0000-0003-2387-5371

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We demonstrate a novel electrowetting liquid combination using a room temperature ionic liquid (RTIL) and a nonpolar liquid, 1-phenyl-1-cyclohexene (PCH) suitable for focus-tunable 3-photon microscopy. We show that both liquids have over 90% transmission at 1300 nm over a 1.1 mm pathlength and an index of refraction contrast of 0.123. A lens using these liquids can be tuned from a contact angle of 133 to 48° with applied voltages of 0 and 60 V, respectively. Finally, a three-photon imaging system including an RTIL electrowetting lens was used to image a mouse brain slice. Axial scans taken with an electrowetting lens show excellent agreement with images acquired using a mechanically scanned objective.

Identifiers

PMID38855666
PMCPMC11161341

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.