Evidence map›Paper›PMID 38855662›Full record

ArticleBiomedical optics express2024

Spectral characterization of a blue light-emitting micro-LED platform on skin-associated microbial chromophores.

Hannah J Serrage, Charlotte J Eling, Pedro U Alves, Enyuan Xie, Andrew J McBain, Martin D Dawson, Catherine O'Neill, Nicolas Laurand

Abstract read
In one paragraph

Article in Biomedical optics express, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. SkinApplied and environmental microbiology · 2026
    Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Hannah J SerrageSchool of Biological Sciences, Faculty of Biology Medicine and Health, The University of Manchester, UK.ORCID https://orcid.org/0000-0002-4995-6076
Charlotte J ElingInstitute of Photonics, Department of Physics, SUPA, University of Strathclyde, UK.
Pedro U AlvesInstitute of Photonics, Department of Physics, SUPA, University of Strathclyde, UK.
Enyuan XieInstitute of Photonics, Department of Physics, SUPA, University of Strathclyde, UK.ORCID https://orcid.org/0000-0001-7776-8091
Andrew J McBainDivision of Pharmacy and Optometry, School of Health Sciences, Faculty of Biology, Medicine and Health, The University of Manchester, UK.
Martin D DawsonInstitute of Photonics, Department of Physics, SUPA, University of Strathclyde, UK.ORCID https://orcid.org/0000-0002-6639-2989
Catherine O'NeillSchool of Biological Sciences, Faculty of Biology Medicine and Health, The University of Manchester, UK.
Nicolas LaurandInstitute of Photonics, Department of Physics, SUPA, University of Strathclyde, UK.ORCID https://orcid.org/0000-0003-0486-4300

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The therapeutic application of blue light (380 - 500nm) has garnered considerable attention in recent years as it offers a non-invasive approach for the management of prevalent skin conditions including acne vulgaris and atopic dermatitis. These conditions are often characterised by an imbalance in the microbial communities that colonise our skin, termed the skin microbiome. In conditions including acne vulgaris, blue light is thought to address this imbalance through the selective photoexcitation of microbial species expressing wavelength-specific chromophores, differentially affecting skin commensals and thus altering the relative species composition. However, the abundance and diversity of these chromophores across the skin microbiota remains poorly understood. Similarly, devices utilised for studies are often bulky and poorly characterised which if translated to therapy could result in reduced patient compliance. Here, we present a clinically viable micro-LED illumination platform with peak emission 450 nm (17 nm FWHM) and adjustable irradiance output to a maximum 0.55 ± 0.01 W/cm

Identifiers

PMID38855662
PMCPMC11161378

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.