Evidence map›Paper›PMID 38855500›Full record

ArticleCornea open2023

Pathogen Profiles of Infectious Conjunctivitis in Ho Chi Minh City, Vietnam.

Huy Tran, Linh Hoang, Yen Tran, Thảo Hạ, Kevin Ruder, Lina Zhong, Cindi Chen, Danny Yu, YuHeng Liu, Thomas Abraham and 6 more

Abstract read
In one paragraph

Article in Cornea open, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Huy TranHai Yen Vision Institute, Ho Chi Minh City, Vietnam.
Linh HoangHai Yen Vision Institute, Ho Chi Minh City, Vietnam.
Yen TranHai Yen Vision Institute, Ho Chi Minh City, Vietnam.
Thảo HạHai Yen Vision Institute, Ho Chi Minh City, Vietnam.
Kevin RuderFrancis I. Proctor Foundation, University of California, San Francisco, USA.
Lina ZhongFrancis I. Proctor Foundation, University of California, San Francisco, USA.
Cindi ChenFrancis I. Proctor Foundation, University of California, San Francisco, USA.
Danny YuFrancis I. Proctor Foundation, University of California, San Francisco, USA.
YuHeng LiuFrancis I. Proctor Foundation, University of California, San Francisco, USA.
Thomas AbrahamFrancis I. Proctor Foundation, University of California, San Francisco, USA.
Armin HinterwirthFrancis I. Proctor Foundation, University of California, San Francisco, USA.
Michael DeinerDepartment of Ophthalmology, University of California, San Francisco, USA.
Travis PorcoFrancis I. Proctor Foundation, University of California, San Francisco, USA.
Thomas M LietmanFrancis I. Proctor Foundation, University of California, San Francisco, USA.
Gerami D SeitzmanFrancis I. Proctor Foundation, University of California, San Francisco, USA.
Thuy DoanFrancis I. Proctor Foundation, University of California, San Francisco, USA.

Funding

UCSF-Proctor Clinician Vision Scholars K12 ProgramK12EY031372 · NEI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI THOMAS M LIETMAN, Yvonne Ou · 2020 to 2026
$3.9M
Seasonal Conjunctivitis Outbreak Reporting for Prevention and Improved Outcomes (SCORPIO)R01EY032041 · NEI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI DOAN, THUY A · 2021 to 2025
$2.0M
NEI NIH HHS K12 EY031372NEI NIH HHS R01 EY032041
6 · The paper itself

Abstract

Purpose: Conjunctivitis epidemics and pandemics remain a global burden. This study aims to comprehensively identify pathogens associated with conjunctivitis in Vietnam. Methods: Patients with acute conjunctivitis presented to an outpatient clinic in Ho Chi Minh City, Vietnam, were enrolled from September 2022 to March 2023. Swabs were obtained from conjunctiva and anterior nares of all patients. Unbiased RNA deep sequencing (RNA-seq) was used to identify any replicating pathogens in the samples. Results: Samples from 35 patients were analyzed. A pathogen was identified in 80% of the patients. 72% (95% confidence interval: 54% to 85%) were infected with either HAdV-D or HAdV-B. RNA viruses detected were rhinoviruses and human coronavirus 229E. Bacteria etiologies included Conclusions: Human adenoviruses are the common circulating pathogens associated with infectious conjunctivitis in Vietnam. HAdV species, however, appear to vary between geographic locations within Vietnam. Other under-recognized pathogens identified in this study, such as RNA viruses, suggest broader pathogen surveillance may be beneficial.

Indexed as

conjunctivitisoutbreaksRNA-seqSCORPIOsurveillanceVietnam

Identifiers

PMID38855500
PMCPMC11160933

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.