Evidence map›Paper›PMID 38855458›Full record

ArticleFrontiers in public health2024

Mathematical modeling of SARS-CoV-2 variant substitutions in European countries: transmission dynamics and epidemiological insights.

Víctor López de Rioja, Aida Perramon-Malavez, Sergio Alonso, Cristina Andrés, Andrés Antón, Antoni E Bordoy, Jordi Càmara, Pere-Joan Cardona, Martí Català, Daniel López and 5 more

Abstract read
In one paragraph

Article in Frontiers in public health, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Observational
  2. Article
  3. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Víctor López de RiojaComputational Biology and Complex Systems Group, Department of Physics, Universitat Politècnica de Catalunya, Barcelona, Spain.
Aida Perramon-MalavezComputational Biology and Complex Systems Group, Department of Physics, Universitat Politècnica de Catalunya, Barcelona, Spain.
Sergio AlonsoComputational Biology and Complex Systems Group, Department of Physics, Universitat Politècnica de Catalunya, Barcelona, Spain.
Cristina AndrésMicrobiology Department, Vall D'Hebron Hospital Universitari, Vall D'Hebron Institut de Recerca, Vall D'Hebron Barcelona Hospital Campus, Barcelona, Spain.
Andrés AntónMicrobiology Department, Vall D'Hebron Hospital Universitari, Vall D'Hebron Institut de Recerca, Vall D'Hebron Barcelona Hospital Campus, Barcelona, Spain.
Antoni E BordoyMicrobiology Department, Northern Metropolitan Clinical Laboratory, Germans Trias i Pujol University Hospital and Research Institute, Badalona, Spain.
Jordi CàmaraMicrobiology Department, Hospital Universitari de Bellvitge, IDIBELL-UB, L'Hospitalet de Llobregat, Barcelona, Spain.
Pere-Joan CardonaMicrobiology Department, Northern Metropolitan Clinical Laboratory, Germans Trias i Pujol University Hospital and Research Institute, Badalona, Spain.
Martí CatalàCentre for Statistics in Medicine, Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, United Kingdom.
Daniel LópezComputational Biology and Complex Systems Group, Department of Physics, Universitat Politècnica de Catalunya, Barcelona, Spain.
Sara MartíMicrobiology Department, Hospital Universitari de Bellvitge, IDIBELL-UB, L'Hospitalet de Llobregat, Barcelona, Spain.
Elisa MartróMicrobiology Department, Northern Metropolitan Clinical Laboratory, Germans Trias i Pujol University Hospital and Research Institute, Badalona, Spain.
Verónica SaludesMicrobiology Department, Northern Metropolitan Clinical Laboratory, Germans Trias i Pujol University Hospital and Research Institute, Badalona, Spain.
Clara PratsComputational Biology and Complex Systems Group, Department of Physics, Universitat Politècnica de Catalunya, Barcelona, Spain.
Enrique Alvarez-LacalleComputational Biology and Complex Systems Group, Department of Physics, Universitat Politècnica de Catalunya, Barcelona, Spain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Countries across Europe have faced similar evolutions of SARS-CoV-2 variants of concern, including the Alpha, Delta, and Omicron variants. Materials and methods: We used data from GISAID and applied a robust, automated mathematical substitution model to study the dynamics of COVID-19 variants in Europe over a period of more than 2 years, from late 2020 to early 2023. This model identifies variant substitution patterns and distinguishes between residual and dominant behavior. We used weekly sequencing data from 19 European countries to estimate the increase in transmissibility Results: Our model accurately reproduced the observed substitution patterns between the Alpha, Delta, and Omicron major variants. We estimated the daily variant prevalence and calculated Conclusion: The use of mathematical models allows for precise and reliable estimation of daily cases of each variant. By quantifying

Indexed as

COVID-19Models, TheoreticalSARS-CoV-2EuropeHumanseffective reproduction numberepidemiological modelingepidemiological timinggenomic surveillanceSARS-COV-2 variantstransmissibilityvaccination ratesvariant substitution

Identifiers

PMID38855458
PMCPMC11160439

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.