Evidence map›Paper›PMID 38855428›Full record

ArticleRadiology advances2024

Seven tesla knee MRI T2*-mapping detects intrasubstance meniscus degeneration in patients with posterior root tears.

Abdul Wahed Kajabi, Štefan Zbýň, Jesse S Smith, Eisa Hedayati, Karsten Knutsen, Luke V Tollefson, Morgan Homan, Hasan Abbasguliyev, Takashi Takahashi, Gregor J Metzger and 2 more

Abstract read
In one paragraph

Article in Radiology advances, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it.

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  8. Imaging Studies of the Stifle Joint inVeterinary sciences · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Abdul Wahed KajabiCenter for Magnetic Resonance Research, University of Minnesota, Minneapolis, MN, 55455, United States.ORCID https://orcid.org/0000-0001-7670-8134
Štefan ZbýňCenter for Magnetic Resonance Research, University of Minnesota, Minneapolis, MN, 55455, United States.
Jesse S SmithCenter for Magnetic Resonance Research, University of Minnesota, Minneapolis, MN, 55455, United States.
Eisa HedayatiCenter for Magnetic Resonance Research, University of Minnesota, Minneapolis, MN, 55455, United States.
Karsten KnutsenCenter for Magnetic Resonance Research, University of Minnesota, Minneapolis, MN, 55455, United States.
Luke V TollefsonTwin Cities Orthopedics, Edina, MN, 55435, United States.
Morgan HomanTwin Cities Orthopedics, Edina, MN, 55435, United States.
Hasan AbbasguliyevDepartment of Diagnostic and Interventional Radiology, Ataturk University Research Hospital, Erzurum, 25240, Türkiye.
Takashi TakahashiDepartment of Radiology, University of Minnesota, Minneapolis, MN, 55455, United States.
Gregor J MetzgerCenter for Magnetic Resonance Research, University of Minnesota, Minneapolis, MN, 55455, United States.
Robert F LaPradeTwin Cities Orthopedics, Edina, MN, 55435, United States.
Jutta M EllermannCenter for Magnetic Resonance Research, University of Minnesota, Minneapolis, MN, 55455, United States.

Funding

TRD4 - Ultrahigh Field Engineering and SafetyP41EB027061 · NIBIB · UNIVERSITY OF MINNESOTA · PI Gregory John Metzger, KAMIL UGURBIL · 2019 to 2026
$11.7M
Advanced 7 Tesla imaging of the knee for root cause of OsteoarthritisR01EB034575 · NIBIB · UNIVERSITY OF MINNESOTA · PI Jutta M Ellermann, Gregory John Metzger · 2023 to 2026
$2.1M
7 Tesla Terra InstrumentS10OD025256 · OD · UNIVERSITY OF MINNESOTA · PI HAREL, NOAM · 2018 to 2018
$2.0M
NIBIB NIH HHS P41 EB027061NIBIB NIH HHS R01 EB034575NIH HHS S10 OD025256
6 · The paper itself

Abstract

Background: Medial meniscus root tears often lead to knee osteoarthritis. The extent of meniscal tissue changes beyond the localized root tear is unknown. Purpose: To evaluate if 7 Tesla 3D T2*-mapping can detect intrasubstance meniscal degeneration in patients with arthroscopically verified medial meniscus posterior root tears (MMPRTs), and assess if tissue changes extend beyond the immediate site of the posterior root tear detected on surface examination by arthroscopy. Methods: In this prospective study we acquired 7 T knee MRIs from patients with MMPRTs and asymptomatic controls. Using a linear mixed model, we compared T2* values between patients and controls, and across different meniscal regions. Patients underwent arthroscopic assessment before MMPRT repair. Changes in pain levels before and after repair were calculated using Knee Injury & Osteoarthritis Outcome Score (KOOS). Pain changes and meniscal extrusion were correlated with T2* using Pearson correlation ( Results: Twenty patients (mean age 53 ± 8; 16 females) demonstrated significantly higher T2* values across the medial meniscus (anterior horn, posterior body and posterior horn: all Conclusions: Elevated T2* values across both medial and lateral menisci indicate that degenerative changes in patients with MMPRTs extend beyond the immediate vicinity of the posterior root tear. This suggests more widespread meniscal degeneration, often undetected by surface examinations in arthroscopy.

Indexed as

7Tmeniscusroot tearT2*-mappingultra-high field MRI

Identifiers

PMID38855428
PMCPMC11159571

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.