Evidence map›Paper›PMID 38855174›Full record

ArticleTheranostics2024

PSMA-targeted radiotheranostics in modern nuclear medicine: then, now, and what of the future?

Mohamed Sallam, Nam-Trung Nguyen, Frank Sainsbury, Nobuo Kimizuka, Serge Muyldermans, Martina Benešová-Schäfer

Abstract readHistorical Article
In one paragraph

Article in Theranostics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Beyond [BMC cancer · 2026
    Pooled it
  2. Review
  3. Article
  4. Review
  5. Article
  6. [European journal of nuclear medicine and molecular imaging · 2026
    Article
  7. Article
  8. Safety and efficacy of [European journal of nuclear medicine and molecular imaging · 2026
    Article
  9. Pharmaceuticals (Basel, Switzerland) · 2026
    Review
  10. Preclinical Evaluation Study ofChemical & biomedical imaging · 2026
    Article
  11. Review
  12. Review
  13. Review
  14. Review
  15. NeoadjuvantCancers · 2025
    Review
  16. Article
  17. Article
  18. Review
  19. Radionuclides Landscape in Prostate Cancer Theranostics.International journal of molecular sciences · 2025
    Review
  20. Development of [Journal of medicinal chemistry · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Mohamed SallamQueensland Micro- and Nanotechnology Centre (QMNC), Griffith University, Nathan Campus, Nathan, QLD 4111, Australia.
Nam-Trung NguyenQueensland Micro- and Nanotechnology Centre (QMNC), Griffith University, Nathan Campus, Nathan, QLD 4111, Australia.
Frank SainsburySchool of Environment and Science (ESC), Griffith University, Nathan Campus, Nathan, QLD 4111, Australia.
Nobuo KimizukaDepartment of Applied Chemistry, Graduate School of Engineering, Kyushu University, 744 Moto-oka, Nishi-ku, Fukuoka 819-0395, Japan.
Serge MuyldermansLaboratory of Cellular and Molecular Immunology (CMIM), Vrije Universiteit Brussel, 1050 Brussels, Belgium.
Martina Benešová-SchäferResearch Group Molecular Biology of Systemic Radiotherapy, German Cancer Research Center (DKFZ), Im Neuenheimer Feld 280, 69120 Heidelberg, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In 1853, the perception of prostate cancer (PCa) as a rare ailment prevailed, was described by the eminent Londoner surgeon John Adams. Rapidly forward to 2018, the landscape dramatically altered. Currently, men face a one-in-nine lifetime risk of PCa, accentuated by improved diagnostic methods and an ageing population. With more than three million men in the United States alone grappling with this disease, the overall risk of succumbing to stands at one in 39. The intricate clinical and biological diversity of PCa poses serious challenges in terms of imaging, ongoing monitoring, and disease management. In the field of theranostics, diagnostic and therapeutic approaches that harmoniously merge targeted imaging with treatments are integrated. A pivotal player in this arena is radiotheranostics, employing radionuclides for both imaging and therapy, with prostate-specific membrane antigen (PSMA) at the forefront. Clinical milestones have been reached, including FDA- and/or EMA-approved PSMA-targeted radiodiagnostic agents, such as [

Indexed as

Antigens, SurfaceGlutamate Carboxypeptidase IIProstatic NeoplasmsRadiopharmaceuticalsHistory, 20th CenturyHistory, 21st CenturyHumansMaleNuclear MedicineRadioisotopesTheranostic NanomedicineAntigens, SurfaceFOLH1 protein, humanGlutamate Carboxypeptidase IIRadioisotopesRadiopharmaceuticalsAntibodiesInhibitorsMetastatic castration-resistant prostate cancerMetastatic hormone-sensitive prostate cancerNanoparticlesNuclear medicineProstate cancerProstate-specific membrane antigenPSMA-targeted theranosticsRadiotheranostics

Identifiers

PMID38855174
PMCPMC11155394

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.