Evidence map›Paper›PMID 38855149›Full record

ArticleWorld journal of gastroenterology2024

Excess non-COVID-19-related mortality among inflammatory bowel disease decedents during the COVID-19 pandemic.

Sarah Rotondo-Trivette, Xin-Yuan He, Jamil S Samaan, Fan Lv, Emily Truong, Michaela Juels, Anthony Nguyen, Xu Gao, Jian Zu, Yee Hui Yeo and 2 more

Abstract read
In one paragraph

Article in World journal of gastroenterology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Sarah Rotondo-TrivetteDepartment of Medicine, Cedars-Sinai Medical Center, Los Angeles, CA 90048, United States.
Xin-Yuan HeDepartment of Infectious Disease, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an 710004, Shaanxi Province, China.
Jamil S SamaanKarsh Division of Gastroenterology and Hepatology Department of Medicine, Cedars-Sinai Medical Center, Los Angeles, CA 90048, United States.
Fan LvSchool of Mathematics and Statistics, Xi'an Jiaotong University, Xi'an 710049, Shaanxi Province, China.
Emily TruongKarsh Division of Gastroenterology and Hepatology Department of Medicine, Cedars-Sinai Medical Center, Los Angeles, CA 90048, United States.
Michaela JuelsDavid Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA 90095, United States.
Anthony NguyenDavid Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA 90095, United States.
Xu GaoDepartment of Infectious Disease, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an 710004, Shaanxi Province, China.
Jian ZuSchool of Mathematics and Statistics, Xi'an Jiaotong University, Xi'an 710049, Shaanxi Province, China.
Yee Hui YeoKarsh Division of Gastroenterology and Hepatology Department of Medicine, Cedars-Sinai Medical Center, Los Angeles, CA 90048, United States.
Fan-Pu JiDepartment of Infectious Disease, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an 710004, Shaanxi Province, China.
Gil Y MelmedKarsh Division of Gastroenterology and HepatologyDepartment of Medicine, Cedars-Sinai Medical Center, Los Angeles, CA 90048, United States. gil.melmed@cshs.org.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe coronavirus disease 2019 (COVID-19) pandemic disrupted healthcare in the United States.

aimTo investigate COVID-19-related and non-COVID-19-related death and characteristics associated with excess death among inflammatory bowel disease (IBD) decedents.

methodsWe performed a register-based study using data from the National Vital Statistics System, which reports death data from over 99% of the United States population, from January 1, 2006 through December 31, 2021. IBD-related deaths among adults 25 years and older were stratified by age, sex, race/ethnicity, place of death, and primary cause of death. Predicted and actual age-standardized mortality rates (ASMRs) per 100000 persons were compared.

results49782 IBD-related deaths occurred during the study period. Non-COVID-19-related deaths increased by 13.14% in 2020 and 18.12% in 2021 [2020 ASMR: 1.55 actual

conclusionIBD patients suffered excess non-COVID-19-related death during the pandemic. Excess death was associated with younger age among UC patients, and with NHB race among CD patients. Increased death at home or on arrival and due to neoplasms suggests that delayed presentation and difficulty accessing healthcare may have led to increased IBD mortality.

Indexed as

Cause of DeathCOVID-19Inflammatory Bowel DiseasesAdultAgedAged, 80 and overAge FactorsColitis, UlcerativeCrohn DiseaseFemaleHumansMaleMiddle AgedPandemicsRegistriesSARS-CoV-2COVID-19Crohn’s diseaseDisparitiesExcess deathInflammatory bowel diseaseRaceSexUlcerative colitis

Identifiers

PMID38855149
PMCPMC11154683

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.