Evidence map›Paper›PMID 38855114›Full record

ArticleFrontiers in immunology2024

Association of specific

Noha M Elemam, Amal Bouzid, Habiba Alsafar, Samrein Bm Ahmed, Shirin Hafezi, Thenmozhi Venkatachalam, Leen Eldohaji, Tasneem Al Hamidi, Peter Habib Gerges, Nour Halabi and 8 more

Abstract read
In one paragraph

Article in Frontiers in immunology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Noha M Elemam *Research Institute for Medical and Health Sciences, University of Sharjah, Sharjah, United Arab Emirates.
Amal Bouzid *Research Institute for Medical and Health Sciences, University of Sharjah, Sharjah, United Arab Emirates.
Habiba AlsafarCenter for Biotechnology, Khalifa University of Science and Technology, Abu Dhabi, United Arab Emirates.
Samrein Bm AhmedResearch Institute for Medical and Health Sciences, University of Sharjah, Sharjah, United Arab Emirates.
Shirin HafeziResearch Institute for Medical and Health Sciences, University of Sharjah, Sharjah, United Arab Emirates.
Thenmozhi VenkatachalamResearch Institute for Medical and Health Sciences, University of Sharjah, Sharjah, United Arab Emirates.
Leen EldohajiResearch Institute for Medical and Health Sciences, University of Sharjah, Sharjah, United Arab Emirates.
Tasneem Al HamidiResearch Institute for Medical and Health Sciences, University of Sharjah, Sharjah, United Arab Emirates.
Peter Habib GergesSchool of Information Technology and Computer Science (ITCS), Nile University, Giza, Egypt.
Nour HalabiAl Jalila Genomics Center of Excellence, Al Jalila Children's Specialty Hospital, Dubai, United Arab Emirates.
Hassen Hadj-KacemDepartment of Applied Biology, College of Sciences, University of Sharjah, Sharjah, United Arab Emirates.
Iman M TalaatResearch Institute for Medical and Health Sciences, University of Sharjah, Sharjah, United Arab Emirates.
Jalal TaneeraResearch Institute for Medical and Health Sciences, University of Sharjah, Sharjah, United Arab Emirates.
Nabil SulaimanResearch Institute for Medical and Health Sciences, University of Sharjah, Sharjah, United Arab Emirates.
Azzam A MaghazachiResearch Institute for Medical and Health Sciences, University of Sharjah, Sharjah, United Arab Emirates.
Qutayba HamidResearch Institute for Medical and Health Sciences, University of Sharjah, Sharjah, United Arab Emirates.
Rifat HamoudiResearch Institute for Medical and Health Sciences, University of Sharjah, Sharjah, United Arab Emirates.
Maha Saber-AyadResearch Institute for Medical and Health Sciences, University of Sharjah, Sharjah, United Arab Emirates.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: The COVID-19 pandemic represented one of the most significant challenges to researchers and healthcare providers. Several factors determine the disease severity, whereas none alone can explain the tremendous variability. The Single nucleotide variants (SNVs) in angiotensin-converting enzyme-2 Methods: We compiled a panel of gene variants from both genes and used Results: Our results showed that the Emirati population lacks the variants that were previously reported as associated with disease severity, whereas a new variant in Conclusion: Whereas COVID-19 represents now a past pandemic, our study underscores the importance of genetic factors specific to a population, which can influence both the susceptibility to viral infections and the level of severity; subsequently expected required preparedness in different areas of the world.

Indexed as

Angiotensin-Converting Enzyme 2COVID-19CytokinesPolymorphism, Single NucleotideSARS-CoV-2Serine EndopeptidasesAdultAgedFemaleHumansMaleMiddle AgedRetrospective StudiesSeverity of Illness IndexUnited Arab EmiratesACE2 protein, humanAngiotensin-Converting Enzyme 2CytokinesSerine EndopeptidasesTMPRSS2 protein, humancoronaviruscytokinegene associationpopulation geneticsprognostic modelsite-direct mutagenesis

Identifiers

PMID38855114
PMCPMC11157456

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.