Evidence map›Paper›PMID 38854944›Full record

ArticleTranslational lung cancer research2024

A novel

Douglas Dias E Silva, Isa Mambetsariev, Jeremy Fricke, Razmig Babikian, Shaira Therese Dingal, Farhad Mazdisnian, Behnam Badie, Leonidas Arvanitis, Michelle Afkhami, Miguel Villalona-Calero and 1 more

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Translational lung cancer research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Douglas Dias E SilvaDepartment of Medical Oncology and Therapeutic Research, City of Hope National Medical Center, Duarte, CA, USA.
Isa MambetsarievDepartment of Medical Oncology and Therapeutic Research, City of Hope National Medical Center, Duarte, CA, USA.
Jeremy FrickeDepartment of Medical Oncology and Therapeutic Research, City of Hope National Medical Center, Duarte, CA, USA.
Razmig BabikianDepartment of Medical Oncology and Therapeutic Research, City of Hope National Medical Center, Duarte, CA, USA.
Shaira Therese DingalDepartment of Medical Oncology and Therapeutic Research, City of Hope National Medical Center, Duarte, CA, USA.
Farhad MazdisnianDepartment of Medicine, City of Hope, Duarte, CA, USA.
Behnam BadieDepartment of Surgery, City of Hope, Duarte, CA, USA.
Leonidas ArvanitisDepartment of Pathology, City of Hope, Duarte, CA, USA.
Michelle AfkhamiDepartment of Pathology, City of Hope, Duarte, CA, USA.
Miguel Villalona-CaleroDepartment of Medical Oncology and Therapeutic Research, City of Hope National Medical Center, Duarte, CA, USA.
Ravi SalgiaDepartment of Medical Oncology and Therapeutic Research, City of Hope National Medical Center, Duarte, CA, USA.ORCID https://orcid.org/0000-0001-9643-7626

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Case Description: A 73-year-old female was initially started on carboplatin, pemetrexed and pembrolizumab with maintenance, but eventually had progression in the left upper lobe (LUL). Upon progression she was enrolled in a clinical trial of a monoclonal antibody with or without a PD-1 inhibitor, but brain metastasis progression was eventually detected by magnetic resonance imaging (MRI) requiring stereotactic radiosurgery (SRS) and a craniotomy. The trial drug was eventually discontinued due to progression and toxicity and NGS on bronchoscopy tissue revealed Conclusions: The positive response to tepotinib of a patient with NSCLC harboring a novel

Indexed as

case reportHLA-DQB2::MET fusionNon-small cell lung cancer (NSCLC)targeted therapytepotinib

Identifiers

PMID38854944
PMCPMC11157375

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.