Evidence map›Paper›PMID 38854863›Full record

ArticleThe Pan African medical journal2024

Sero-prevalence of syphilis and associated risk factors among pregnant women attending antenatal care at an urban-poor health centre in Kampala, Uganda: a cross-sectional study.

Andrew Simiyu, Collins Grace Kalanga Atuheire, Martha Taremwa, Sarah Nabwire Ssali, Frank Norbert Mwiine, Clovice Kankya, Kizito Kahooza Mugimba

Abstract read
In one paragraph

Article in The Pan African medical journal, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Andrew SimiyuDepartment of Biosecurity, Ecosystems and Veterinary Public Health (School of Biosecurity, Biotechnology and Laboratory Sciences (SBLS)), College of Veterinary Medicine, Animal Resources and Biosecurity, Makerere University, Kampala, Uganda.
Collins Grace Kalanga AtuheireDepartment of Biosecurity, Ecosystems and Veterinary Public Health (School of Biosecurity, Biotechnology and Laboratory Sciences (SBLS)), College of Veterinary Medicine, Animal Resources and Biosecurity, Makerere University, Kampala, Uganda.
Martha TaremwaDepartment of Biosecurity, Ecosystems and Veterinary Public Health (School of Biosecurity, Biotechnology and Laboratory Sciences (SBLS)), College of Veterinary Medicine, Animal Resources and Biosecurity, Makerere University, Kampala, Uganda.
Sarah Nabwire SsaliSchool of Women and Gender Studies, College of Humanities, Makerere University, Kampala, Uganda.
Frank Norbert MwiineDepartment of Biomolecular and Biolaboratory Sciences (School of Biosecurity, Biotechnology and Laboratory Sciences (SBLS)), College of Veterinary Medicine, Animal Resources and Biosecurity, Makerere University, Kampala, Uganda.
Clovice KankyaDepartment of Biosecurity, Ecosystems and Veterinary Public Health (School of Biosecurity, Biotechnology and Laboratory Sciences (SBLS)), College of Veterinary Medicine, Animal Resources and Biosecurity, Makerere University, Kampala, Uganda.
Kizito Kahooza MugimbaDepartment of Biomolecular and Biolaboratory Sciences (School of Biosecurity, Biotechnology and Laboratory Sciences (SBLS)), College of Veterinary Medicine, Animal Resources and Biosecurity, Makerere University, Kampala, Uganda.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: syphilis and its outcomes remain a healthcare system burden with adverse consequences such as stillbirths, neonatal deaths and spontaneous abortions among others. The situation might have worsened because the COVID-19 pandemic has caused a major attention drift from other diseases. Additionally, much as testing for syphilis is a routine practice among pregnant mothers, its proportion is not known in urban health care setting. A study to determine the prevalence of syphilis among pregnant mothers in an urban poor setting is warranted. Methods: a cross-sectional study was conducted among pregnant women who attended antenatal care at Kawaala Health Centre IV in Kampala Capital City between December 2019 to March 2020. Informed consent was sought from study participants prior to data collection using structured questionnaires. Whole blood was collected and tested using SD Bioline HIV/syphilis duo rapid test kit (SD Standard Diagnostics, INC, Korea). Data analysis was done using STATA 14.2. Results: one thousand one hundred and sixty-nine pregnant women participated in the study, with a mean age of 25 years. About 27% of them had completed only primary-level education. Approximately 6% of the participants were HIV seropositive. The prevalence of syphilis was 5.9% (69/1169). HIV positivity (aOR: 4.13, 95%CI: 2.05-8.34), elevated blood pressure (aOR: 2.84, 95%CI: 1.42-5.69), and status of previous pregnancy (aOR: 0.21, 95%CI: 0.05-0.89) were significant predictors of the risk of syphilis among pregnant women in this setting. Conclusion: the prevalence of syphilis among pregnant women in urban poor settings is not low and so must not be underestimated. The potential drivers of syphilis among pregnant women are HIV, elevated blood pressure, and status of previous pregnancy. There should be increased awareness about routine syphilis testing among pregnant mothers attending antenatal care.

Indexed as

Pregnancy Complications, InfectiousPrenatal CareSyphilisAdolescentAdultCross-Sectional StudiesFemaleHIV InfectionsHumansPregnancyPrevalenceRisk FactorsSeroepidemiologic StudiesUgandaUrban PopulationYoung AdultHIVpregnant womenrisk factorsSyphilis

Identifiers

PMID38854863
PMCPMC11161699

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.