Evidence map›Paper›PMID 38854794›Full record

ArticlePeerJ2024

Predictive value of plasma ephrinB2 levels for amputation risk following endovascular revascularization in peripheral artery disease.

Pengcheng Guo, Lei Chen, Dafeng Yang, Lei Zhang, Chang Shu, Huande Li, Jieting Zhu, Jienan Zhou, Xin Li

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in PeerJ, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Pengcheng GuoVascular Surgery Department, the Secondary Xiangya Hospital, Central South University, Hunan, China.
Lei ChenPharmacy Department, the Secondary Xiangya Hospital, Central South University, Hunan, China.
Dafeng YangCardiology Surgery Department, the Secondary Xiangya Hospital, Central South University, Hunan, China.ORCID 0000-0002-8320-8215
Lei ZhangVascular Surgery Department, the Secondary Xiangya Hospital, Central South University, Hunan, China.
Chang ShuVascular Surgery Department, the Secondary Xiangya Hospital, Central South University, Hunan, China.
Huande LiPharmacy Department, the Secondary Xiangya Hospital, Central South University, Hunan, China.
Jieting ZhuVascular Surgery Department, the Secondary Xiangya Hospital, Central South University, Hunan, China.
Jienan ZhouVascular Surgery Department, the Secondary Xiangya Hospital, Central South University, Hunan, China.
Xin LiVascular Surgery Department, the Secondary Xiangya Hospital, Central South University, Hunan, China.

Funding

Central South University Research Program of Advanced Interdisciplinary StudiesNational Natural Science Foundation of China (NSFC)
6 · The paper itself

Abstract

Background: The aim of this study is to investigate the expression levels of ephrinB2 in patients with lower extremity peripheral arterial disease (PAD) and explore its association with the severity of the disease and the risk of amputation after endovascular revascularization. Methods: During the period from March 2021 to March 2023, this study collected blood samples and clinical data from 133 patients diagnosed with lower extremity PAD and 51 healthy volunteer donors. The severity of lower extremity PAD patients was classified using the Rutherford categories. The expression of ephrin-B2 in plasma samples was detected using the Western Blotting. Results: Compared to the control group, the levels of serum ephrinB2 in patients were significantly elevated ( Conclusions: Plasma EphrinB2 levels may be linked to lower extremity PAD development, inflammation, and postoperative amputation. Combining EphrinB2 and NLR can improve amputation prediction accuracy after endovascular revascularization in lower extremity PAD patients.

Indexed as

Endovascular ProceduresEphrin-B2Peripheral Arterial DiseaseAgedAmputation, SurgicalBiomarkersCase-Control StudiesFemaleHumansLower ExtremityMaleMiddle AgedNeutrophilsPredictive Value of TestsRisk FactorsSeverity of Illness IndexBiomarkersEFNB2 protein, humanEphrin-B2Amputation riskEphrinB2Peripheral arterial diseaseRevascularization

Identifiers

PMID38854794
PMCPMC11162178

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.