Evidence map›Paper›PMID 38854718›Full record

ArticleFrontiers in oncology2024

Assessing the role of advanced artificial intelligence as a tool in multidisciplinary tumor board decision-making for primary head and neck cancer cases.

Benedikt Schmidl, Tobias Hütten, Steffi Pigorsch, Fabian Stögbauer, Cosima C Hoch, Timon Hussain, Barbara Wollenberg, Markus Wirth

Abstract read
In one paragraph

Article in Frontiers in oncology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
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  10. A Comparative Analysis of GPT-4o and ERNIE Bot in a Chinese Radiation Oncology Exam.Journal of cancer education : the official journal of the American Association for Cancer Education · 2026
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  14. On critical thinking in times of standardisation.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2025
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  17. ChatGPT versus DeepSeek in head and neck cancer staging and treatment planning: guideline-based study.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Benedikt SchmidlDepartment of Otolaryngology Head and Neck Surgery, Technical University Munich, Munich, Germany.
Tobias HüttenDepartment of Otolaryngology Head and Neck Surgery, Technical University Munich, Munich, Germany.
Steffi PigorschDepartment of RadioOncology, Technical University Munich, Munich, Germany.
Fabian StögbauerInstitute of Pathology, Technical University Munich, Munich, Germany.
Cosima C HochDepartment of Otolaryngology Head and Neck Surgery, Technical University Munich, Munich, Germany.
Timon HussainDepartment of Otolaryngology Head and Neck Surgery, Technical University Munich, Munich, Germany.
Barbara WollenbergDepartment of Otolaryngology Head and Neck Surgery, Technical University Munich, Munich, Germany.
Markus WirthDepartment of Otolaryngology Head and Neck Surgery, Technical University Munich, Munich, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Head and neck squamous cell carcinoma (HNSCC) is a complex malignancy that requires a multidisciplinary approach in clinical practice, especially in tumor board discussions. In recent years, artificial intelligence has emerged as a tool to assist healthcare professionals in making informed decisions. This study investigates the application of ChatGPT 3.5 and ChatGPT 4.0, natural language processing models, in tumor board decision-making. Methods: We conducted a pilot study in October 2023 on 20 consecutive head and neck cancer patients discussed in our multidisciplinary tumor board (MDT). Patients with a primary diagnosis of head and neck cancer were included. The MDT and ChatGPT 3.5 and ChatGPT 4.0 recommendations for each patient were compared by two independent reviewers and the number of therapy options, the clinical recommendation, the explanation and the summarization were graded. Results: In this study, ChatGPT 3.5 provided mostly general answers for surgery, chemotherapy, and radiation therapy. For clinical recommendation, explanation and summarization ChatGPT 3.5 and 4.0 scored well, but demonstrated to be mostly an assisting tool, suggesting significantly more therapy options than our MDT, while some of the recommended treatment modalities like primary immunotherapy are not part of the current treatment guidelines. Conclusions: This research demonstrates that advanced AI models at the moment can merely assist in the MDT setting, since the current versions list common therapy options, but sometimes recommend incorrect treatment options and in the case of ChatGPT 3.5 lack information on the source material.

Indexed as

artificial intelligenceChatGPTHNSCCmultidisciplinary tumor boardradiotherapy

Identifiers

PMID38854718
PMCPMC11157509

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.