Evidence map›Paper›PMID 38854148›Full record

ArticlebioRxiv : the preprint server for biology2024

Genetic background affects the strength of crossover interference in house mice.

Andrew P Morgan, Bret A Payseur

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Andrew P MorganDepartment of Medicine, University of North Carolina, Chapel Hill, NC.ORCID 0000-0003-1942-4543
Bret A PayseurLaboratory of Genetics, University of Wisconsin, Madison, WI.

Funding

Resource Section - Core 001U42OD010924 · OD · UNIV OF NORTH CAROLINA CHAPEL HILL · PI TERRY R MAGNUSON · 2012 to 2026
$24.5M
An Interdisciplinary program for systems genomics of complex behaviorsP50MH090338 · NIMH · UNIV OF NORTH CAROLINA CHAPEL HILL · PI PARDO-MANUEL DE VILLENA, FERNANDO · 2009 to 2010
$6.0M
Evolution of Phenotypic Extremes: Genetic Determinants of Gigantism, Boldness, and RecombinationR35GM139412 · NIGMS · UNIVERSITY OF WISCONSIN-MADISON · PI Bret A. Payseur · 2021 to 2026
$5.7M
An Interdisciplinary program for systems genomics of complex behaviorsP50HG006582 · NHGRI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI PARDO-MANUEL DE VILLENA, FERNANDO · 2011 to 2013
$2.6M
Collaborative Cross: A system genetics approach to the study of male infertilityR01HD065024 · NICHD · UNIV OF NORTH CAROLINA CHAPEL HILL · PI O'BRIEN, DEBORAH A., PARDO-MANUEL DE VILLENA, FERNANDO · 2010 to 2014
$1.7M
Systems Genetics of Fluoxetine-Induced Neurogenesis and Antidepressant ResponseK01MH094406 · NIMH · UNIV OF NORTH CAROLINA CHAPEL HILL · PI CROWLEY, JAMES JOSEPH · 2012 to 2015
$588k
Effect of paternal age on mutational burden and behavior in miceR21MH096261 · NIMH · UNIV OF NORTH CAROLINA CHAPEL HILL · PI PARDO-MANUEL DE VILLENA, FERNANDO · 2012 to 2013
$400k
Effects of advanced paternal age on germline genome stabilityF30MH103925 · NIMH · UNIV OF NORTH CAROLINA CHAPEL HILL · PI MORGAN, ANDREW PARKER · 2014 to 2017
$151k
NHGRI NIH HHS P50 HG006582NICHD NIH HHS R01 HD065024NIGMS NIH HHS R35 GM139412NIH HHS U42 OD010924NIMH NIH HHS F30 MH103925NIMH NIH HHS K01 MH094406NIMH NIH HHS P50 MH090338NIMH NIH HHS R21 MH096261
6 · The paper itself

Abstract

Meiotic recombination is required for faithful chromosome segregation in most sexually reproducing organisms and shapes the distribution of genetic variation in populations. Both the overall rate and the spatial distribution of crossovers vary within and between species. Adjacent crossovers on the same chromosome tend to be spaced more evenly than expected at random, a phenomenon known as crossover interference. Although interference has been observed in many taxa, the factors that influence the strength of interference are not well understood. We used house mice

Identifiers

PMID38854148
PMCPMC11160618

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.