Evidence map›Paper›PMID 38854129›Full record

ArticlebioRxiv : the preprint server for biology2024

Altered liver metabolism post-wean abolishes efficacy of vitamin D for breast cancer prevention in a mouse model.

Sarah M Bernhardt, Michelle K Ozaki, Courtney Betts, Lisa A Bleyle, Andrea E DeBarber, Jaime Fornetti, Abigail L Liberty, Elise Wilde De, Yi Zhang, Zheng Xia and 1 more

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Sarah M BernhardtDepartment of Cell, Developmental & Cancer Biology, Oregon Health & Science University, Portland, OR 97239, USA.
Michelle K OzakiDepartment of Cell, Developmental & Cancer Biology, Oregon Health & Science University, Portland, OR 97239, USA.
Courtney BettsDepartment of Cell, Developmental & Cancer Biology, Oregon Health & Science University, Portland, OR 97239, USA.
Lisa A BleyleBioanalytical Shared Resource/Pharmacokinetics Core Facility, University Shared Resources, Oregon Health & Science University, 3181 SW Sam Jackson Park Road, Portland, OR 97239, USA.
Andrea E DeBarberBioanalytical Shared Resource/Pharmacokinetics Core Facility, University Shared Resources, Oregon Health & Science University, 3181 SW Sam Jackson Park Road, Portland, OR 97239, USA.
Jaime FornettiHuntsman Cancer Institute, University of Utah, Salt Lake City, Utah, 84112, USA.
Abigail L LibertyDivision of Complex Family Planning, Department of Obstetrics & Gynecology, Oregon Health & Science University, Portland, OR, 97239, USA.
Elise Wilde DeDepartment of Cell, Developmental & Cancer Biology, Oregon Health & Science University, Portland, OR 97239, USA.
Yi ZhangComputational Biology Program, Oregon Health & Science University, Portland, OR 97201, USA.
Zheng XiaComputational Biology Program, Oregon Health & Science University, Portland, OR 97201, USA.
Pepper SchedinDepartment of Cell, Developmental & Cancer Biology, Oregon Health & Science University, Portland, OR 97239, USA.

Funding

Understanding the origins of rapid recurrence of pancreatic cancer after resectionP30CA069533 · NCI · OREGON HEALTH & SCIENCE UNIVERSITY · PI Luiz Eduardo Bertassoni · 1997 to 2026
$60.5M
NSAIDs During Postpartum Involution for Breast Cancer ChemopreventionR01CA169175 · NCI · UNIVERSITY OF COLORADO DENVER · PI SCHEDIN, PEPPER J · 2013 to 2024
$4.8M
NCI NIH HHS P30 CA069533NCI NIH HHS R01 CA169175
6 · The paper itself

Abstract

Young women have increased risk of vitamin D deficiency, which may increase breast cancer incidence. Here, we assessed the anti-cancer efficacy of vitamin D in mouse models of young-onset breast cancer. In never-pregnant mice, vitamin D supplementation increased serum 25(OH)D and hepatic 1,25(OH)

Indexed as

liver metabolismmammary gland involutionpostpartum breast cancerVitamin D

Identifiers

PMID38854129
PMCPMC11160686

What OpenQuestion holds

Textmetadata
LicenceCC BY-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.