Evidence map›Paper›PMID 38854126›Full record

ArticlebioRxiv : the preprint server for biology2024

The ABCF ATPase New1 resolves translation termination defects associated with specific tRNA

Kathryn Turnbull, Helge Paternoga, Esther von der Weth, Artyom A Egorov, Agnieszka A Pochopien, Yujie Zhang, Lilit Nersisyan, Tõnu Margus, Marcus J O Johansson, Vicent Pelechano and 2 more

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In one paragraph

Article in bioRxiv : the preprint server for biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

12 authors.

Kathryn TurnbullDepartment of Clinical Microbiology, Rigshospitalet, 2200 Copenhagen, Denmark.ORCID 0000-0002-0899-974X
Helge PaternogaInstitute for Biochemistry and Molecular Biology, University of Hamburg, Martin-Luther-King-Platz 6, 20146 Hamburg, Germany.
Esther von der WethMax Planck Institute of Molecular Cell Biology and Genetics, Dresden, Germany.
Artyom A EgorovDepartment of Experimental Medicine, University of Lund, 221 84 Lund, Sweden.ORCID 0000-0001-5578-5384
Agnieszka A PochopienInstitute for Biochemistry and Molecular Biology, University of Hamburg, Martin-Luther-King-Platz 6, 20146 Hamburg, Germany.
Yujie ZhangSciLifeLab, Department of Microbiology, Tumor and Cell Biology. Karolinska Institutet, Solna, Sweden.
Lilit NersisyanSciLifeLab, Department of Microbiology, Tumor and Cell Biology. Karolinska Institutet, Solna, Sweden.
Tõnu MargusMoisavahe 60-28, 50707 Tartu, Estonia.ORCID 0000-0003-4966-1291
Marcus J O JohanssonDepartment of Experimental Medicine, University of Lund, 221 84 Lund, Sweden.ORCID 0000-0001-7117-7426
Vicent PelechanoSciLifeLab, Department of Microbiology, Tumor and Cell Biology. Karolinska Institutet, Solna, Sweden.ORCID 0000-0002-9415-788X
Daniel N WilsonInstitute for Biochemistry and Molecular Biology, University of Hamburg, Martin-Luther-King-Platz 6, 20146 Hamburg, Germany.ORCID 0000-0003-3816-3828
Vasili HauryliukDepartment of Experimental Medicine, University of Lund, 221 84 Lund, Sweden.ORCID 0000-0003-2389-5057

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The efficiency of translation termination is determined by the nature of the stop codon as well as its context. In eukaryotes, recognition of the A-site stop codon and release of the polypeptide are mediated by release factors eRF1 and eRF3, respectively. Translation termination is modulated by other factors which either directly interact with release factors or bind to the E-site and modulate the activity of the peptidyl transferase center. Previous studies suggested that the

Identifiers

PMID38854126
PMCPMC11160720

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.