Evidence map›Paper›PMID 38854121›Full record

ArticlebioRxiv : the preprint server for biology2024

Distinct mechanisms of non-autonomous UPR

Aeowynn J Coakley, Adam J Hruby, Jing Wang, Andrew Bong, Tripti Nair, Carmen M Ramos, Athena Alcala, Daniel Hicks, Maxim Averbukh, Naibedya Dutta and 9 more

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

19 authors.

Aeowynn J CoakleyLeonard Davis School of Gerontology, University of Southern California, Los Angeles, CA 90089, United States.
Adam J HrubyLeonard Davis School of Gerontology, University of Southern California, Los Angeles, CA 90089, United States.
Jing WangLeonard Davis School of Gerontology, University of Southern California, Los Angeles, CA 90089, United States.
Andrew BongLeonard Davis School of Gerontology, University of Southern California, Los Angeles, CA 90089, United States.
Tripti NairLeonard Davis School of Gerontology, University of Southern California, Los Angeles, CA 90089, United States.
Carmen M RamosLeonard Davis School of Gerontology, University of Southern California, Los Angeles, CA 90089, United States.
Athena AlcalaLeonard Davis School of Gerontology, University of Southern California, Los Angeles, CA 90089, United States.
Daniel HicksLeonard Davis School of Gerontology, University of Southern California, Los Angeles, CA 90089, United States.
Maxim AverbukhLeonard Davis School of Gerontology, University of Southern California, Los Angeles, CA 90089, United States.
Naibedya DuttaLeonard Davis School of Gerontology, University of Southern California, Los Angeles, CA 90089, United States.
Darius MoaddeliLeonard Davis School of Gerontology, University of Southern California, Los Angeles, CA 90089, United States.
Cynthia SiebrandLeonard Davis School of Gerontology, University of Southern California, Los Angeles, CA 90089, United States.
Mattias de Los Rios RogersDepartment of Molecular, Cell, and Developmental Biology, University of California, Los Angeles, CA 90095, United States.
Arushi SahayDepartment of Cell & Molecular Biology, University of Pennsylvania, Philadelphia, PA 19104, United States.
Sean P CurranLeonard Davis School of Gerontology, University of Southern California, Los Angeles, CA 90089, United States.ORCID 0000-0001-7791-6453
Peter J MullenDepartment of Molecular Microbiology and Immunology, Keck School of Medicine, University of Southern California, Los Angeles, CA 90089, United States.
Bérénice A BenayounLeonard Davis School of Gerontology, University of Southern California, Los Angeles, CA 90089, United States.ORCID 0000-0002-7401-4777
Gilberto GarciaLeonard Davis School of Gerontology, University of Southern California, Los Angeles, CA 90089, United States.
Ryo Higuchi-SanabriaLeonard Davis School of Gerontology, University of Southern California, Los Angeles, CA 90089, United States.

Funding

Wormbase SupplementP41HG002223 · NHGRI · CALIFORNIA INSTITUTE OF TECHNOLOGY · PI STERNBERG, PAUL WARREN · 2000 to 2012
$32.0M
WormBase: a core data resource for C. elegans and other nematodesU41HG002223 · NHGRI · CALIFORNIA INSTITUTE OF TECHNOLOGY · PI KERSEY, PAUL, SCHEDL, TIM · 2013 to 2017
$20.5M
WormBase: a core data resource for C. elegans and other nematodesU24HG002223 · NHGRI · CALIFORNIA INSTITUTE OF TECHNOLOGY · PI TIM SCHEDL, PAUL Warren STERNBERG · 2018 to 2026
$18.9M
Enhancing and expanding the CGC Strain CollectionP40OD010440 · OD · UNIVERSITY OF MINNESOTA · PI Aric L Daul, Ann E. Rougvie · 2012 to 2026
$7.5M
USC Geroscience Training in the Biology of AgingT32AG052374 · NIA · UNIVERSITY OF SOUTHERN CALIFORNIA · PI Sean P CURRAN · 2016 to 2026
$5.3M
Age-dependent SKN-1/NRF cytoprotection at the cost of metabolic homeostasisR01AG058610 · NIA · UNIVERSITY OF SOUTHERN CALIFORNIA · PI CURRAN, SEAN P · 2019 to 2023
$2.1M
When actin’s not actin like actin: Nuclear actin impacts transcription and agingR01AG079806 · NIA · UNIVERSITY OF SOUTHERN CALIFORNIA · PI Ryo Higuchi-Sanabria · 2024 to 2026
$1.9M
More than just a load control: cytoskeletal form and function during agingR00AG065200 · NIA · UNIVERSITY OF SOUTHERN CALIFORNIA · PI HIGUCHI-SANABRIA, RYO · 2021 to 2023
$747k
NHGRI NIH HHS P41 HG002223NHGRI NIH HHS U24 HG002223NHGRI NIH HHS U41 HG002223NIA NIH HHS R00 AG065200NIA NIH HHS R01 AG058610NIA NIH HHS R01 AG079806NIA NIH HHS T32 AG052374NIH HHS P40 OD010440
6 · The paper itself

Abstract

The capacity to deal with stress declines during the aging process, and preservation of cellular stress responses is critical to healthy aging. The unfolded protein response of the endoplasmic reticulum (UPR

Indexed as

AgingERneuronsstress

Identifiers

PMID38854121
PMCPMC11160609

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.