Evidence map›Paper›PMID 38854092›Full record

ArticlemedRxiv : the preprint server for health sciences2024

Neuropsychological and social predictors of participation in a deep brain stimulation study of Parkinson's disease and dystonia.

Amelia Hahn, Ann A Lazar, Stephanie Cernera, Simon Little, Sarah S Wang, Philip A Starr, Caroline A Racine

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in medRxiv : the preprint server for health sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Amelia HahnUniversity of California, San Francisco, Department of Neurological Surgery.ORCID 0009-0006-2666-3058
Ann A LazarUniversity of California, San Francisco, Department of Epidemiology and Biostatistics.
Stephanie CerneraUniversity of California, San Francisco, Department of Neurological Surgery.ORCID 0000-0002-6885-6791
Simon LittleUniversity of California, San Francisco, Department of Neurology.ORCID 0000-0001-6249-6230
Sarah S WangUniversity of California, San Francisco, Department of Neurology.
Philip A StarrUniversity of California, San Francisco, Department of Neurological Surgery.ORCID 0000-0003-2733-4003
Caroline A RacineUniversity of California, San Francisco, Department of Neurological Surgery.ORCID 0000-0001-7992-7084

Funding

Clinical and Translational Science InstituteUL1TR001872 · NCATS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI COLLARD, HAROLD R, JACOBY, VANESSA · 2016 to 2025
$112.1M
Closed Loop Deep Brain Stimulation for Parkinson's DiseaseUH3NS100544 · NINDS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI STARR, PHILIP ANDREW · 2016 to 2022
$4.1M
Determining the circuits and signals of sleep dysfunction in Parkinson's disease through chronic intracranial recordings and closed-loop Deep Brain StimulationR01NS131405 · NINDS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Simon Little · 2023 to 2026
$2.6M
NCATS NIH HHS UL1 TR001872NINDS NIH HHS R01 NS131405NINDS NIH HHS UH3 NS100544
6 · The paper itself

Abstract

Objectives: Participation is essential to DBS research, yet circumstances that affect diverse participation remain unclear. Here we evaluate factors impacting participation in an adaptive DBS study of Parkinson's disease (PD) and dystonia. Methods: Twenty participants were implanted with a sensing-enabled DBS device (Medtronic Summit RC+S) that allows neural data streaming in naturalistic settings and encouraged to stream as much as possible for the first five months after surgery. Using standardized baseline data obtained through neuropsychological evaluation, we compared neuropsychological and social variables to streaming hours. Results: Marital status and irritability significantly impacted streaming hours (estimate=136.7, bootstrapped ( Discussion: Verbal memory impairment, irritability, and lack of a caregiver may be associated with decreased participation. Further study of factors that impact research participation is critical to the sustained inclusion of diverse participants.

Indexed as

dystoniaParkinson’s disease (PD)recruitmentresearch participationretention

Identifiers

PMID38854092
PMCPMC11160823

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.