Evidence map›Paper›PMID 38854081›Full record

ArticleResearch square2024

Status-neutral community-based multilevel intervention to address intersectional stigma and discrimination, and increase HIV testing, PrEP, and ART uptake among YGBMSM in Ghanaian Slums: A clustered randomized control trial protocol.

Gamji Rabiu Abu-Ba'are, Kwasi Torpey, Chris Guure, LaRon E Nelson, Sangchoon Jeon, James McMahon, Natalie M Leblanc, Osman Wumpini Shamrock, Edem Yaw Zigah, Amos Apreku and 6 more

Registry-linked trialAbstract readPreprint
In one paragraph

Article in Research square, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06312514 (Status-neutral Community-based Multilevel Intervention to Address Intersectional Stigma and Discrimination, and Increase HIV Testing, PrEP, and ART Uptake Among YGBMSM in Ghanaian Slums), which is not on this map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06312514 nawithdrawnnot on this mapstarted 2025, after this paper: background citation

Status-neutral Community-based Multilevel Intervention to Address Intersectional Stigma and Discrimination, and Increase HIV Testing, PrEP, and ART Uptake Among YGBMSM in Ghanaian Slums: A Clustered Randomized Control Trial Protocol

TypeinterventionalSponsorUniversity of RochesterRan2025 to 2028Enrolled0ConditionsHIV Prevention and CareArmsLAFIYA
3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Gamji Rabiu Abu-Ba'areBehavioral, Sexual, and Global Health Lab, School of Nursing, University of Rochester Medical Center, University of Rochester, New York, USA.ORCID 0000-0002-1718-0381
Kwasi TorpeyDepartment of Population, Family and Reproductive Health, School of Public Health, University of Ghana, Accra, Ghana.ORCID 0000-0003-1628-2922
Chris GuureDepartment of Biostatistics, School of Public Health, University of Ghana, Legon-Accra, Ghana.ORCID 0000-0001-6595-9587
LaRon E NelsonSchool of Nursing, Yale University, New Haven, Connecticut, USA.ORCID 0000-0002-2630-602X
Sangchoon JeonSchool of Nursing, Yale University, New Haven, Connecticut, USA.ORCID 0000-0003-2855-2053
James McMahonSchool of Nursing, University of Rochester Medical Center, University of Rochester, New York, USA.
Natalie M LeblancSchool of Nursing, University of Rochester Medical Center, University of Rochester, New York, USA.ORCID 0000-0002-1804-7718
Osman Wumpini ShamrockBehavioral, Sexual, and Global Health Lab, School of Nursing, University of Rochester Medical Center, University of Rochester, New York, USA.ORCID 0000-0003-3127-9596
Edem Yaw ZigahBehavioral, Sexual, and Global Health Lab, School of Nursing, University of Rochester, Rochester, New York, USA.ORCID 0000-0002-8172-4427
Amos AprekuDepartment of Population, Family and Reproductive Health, School of Public Health, University of Ghana, Accra, Ghana.ORCID 0000-0001-8115-9125
Henry Delali DakpuiBehavioral, Sexual, and Global Health Lab, School of Nursing, University of Rochester Medical Center, University of Rochester, New York, USA.ORCID 0009-0005-8364-1253
George Rudolph Kofi AgbemeduBehavioral, Sexual, and Global Health Lab, School of Nursing, University of Rochester Medical Center, University of Rochester, New York, USA.ORCID 0000-0003-1759-715X
Francis BoakyePriorities on Rights and Sexual Health, Accra, Ghana.
Prince AduPriorities on Rights and Sexual Health, Accra, Ghana.
Andrew AttisoePriorities on Rights and Sexual Health, Accra, Ghana.
Gideon AdjakaHope Alliance Foundation, Accra, Ghana.

Funding

Training Program for Scientists Conducting Research to Reduce HIV Health DisparitR25MH067127 · NIMH · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Emily A Arnold, Torsten Brian Neilands · 2003 to 2026
$5.4M
NIMH NIH HHS R25 MH067127
6 · The paper itself

Abstract

Background: While GBMSM constitute less than 2% of Ghana's population, their HIV prevalence surpasses the national average by more than eightfold, emphasizing the critical need for targeted interventions to improve detection, care linkage, and reduce community transmission. This study seeks to increase HIV testing, Pre-Exposure Prophylaxis (PrEP), and Antiretroviral Therapy (ART) uptake (HPART) among YGBMSM through the adaptation of an evidence-based intervention (LAFIYA). Methodology: We will employ the ADAPTT-IT framework to adapt LAFIYA and evaluate its feasibility and effectiveness in addressing intersectional stigma and increasing HPART uptake among YGBMSM residing in Ghanaian slums. In aim 1, we will hold focus groups (n=5) and interviews (n=20) among YGBMSM and two FGDs among GBMSM-led organizations. At the HCF level, we will hold 6 FGDs and interviews (n=20) among nurses. In AIM 2, we will randomly assign 6 healthcare facilities (HCFs) to receive the LAFIYA (n=3) or wait-list control (n=3). Friend groups (cluster) of YGBMSM (N=240) will be assigned to receive LAFIYA (n=120) or a wait-list control (n=120). We will collect 3-, 6-, and 9-months post-intervention data among YGBMSM(n=240) and HCWs(n=300) to measure HPART adherence (primary outcomes), ISD reduction, HIV and status-neutral knowledge (secondary outcomes), and intervention acceptability, appropriateness, and feasibility (implementation outcomes). Conclusion: The intervention group will observe increased HPART adherence, reduced ISD, and enhanced HPART knowledge and efficacy relative to the wait-list control group. The findings will inform ISD reduction and HIV status-neutral implementation strategies - and place-based interventions that address access to HIV prevention and care among YGBMSM, slum and in different settings. Trail Registration: This study was registered on clinicalTrail.gov, with identifier number NCT06312514 on 03/14/2023. https://classic.clinicaltrials.gov/ct2/show/NCT06312514.

Indexed as

Antiretroviral TherapyHealthcareHIVIntersectional StigmaPre-Exposure ProphylaxisTesting

Identifiers

PMID38854081
PMCPMC11160908

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.