Evidence map›Paper›PMID 38854046›Full record

ArticleResearch square2024

Molecular interplay between HURP and Kif18A in mitotic spindle regulation.

Juan M Perez-Bertoldi, Yuanchang Zhao, Akanksha Thawani, Ahmet Yildiz, Eva Nogales

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in Research square, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors.

Juan M Perez-BertoldiBiophysics Graduate Group, University of California, Berkeley, CA, USA.ORCID 0000-0003-4590-820X
Yuanchang ZhaoPhysics Department, University of California, Berkeley, CA, USA.ORCID 0000-0003-1458-5321
Akanksha ThawaniDepartment of Molecular and Cell Biology, University of California, Berkeley, CA, USA.ORCID 0000-0003-4168-128X
Ahmet YildizBiophysics Graduate Group, University of California, Berkeley, CA, USA.ORCID 0000-0003-4792-174X
Eva NogalesDepartment of Molecular and Cell Biology, University of California, Berkeley, CA, USA.ORCID 0000-0001-9816-3681

Funding

The Mechanism and Regulation of the Dynein Transport MachineryR35GM136414 · NIGMS · UNIVERSITY OF CALIFORNIA BERKELEY · PI Ahmet Yildiz · 2020 to 2026
$5.1M
Structural studies of function and regulation of microtubules and transcriptional gene expression machineryR35GM127018 · NIGMS · UNIVERSITY OF CALIFORNIA BERKELEY · PI Eva Nogales · 2018 to 2026
$4.3M
NIGMS NIH HHS R35 GM127018NIGMS NIH HHS R35 GM136414
6 · The paper itself

Abstract

During mitosis, microtubule dynamics are regulated to ensure proper alignment and segregation of chromosomes. The dynamics of kinetochore-attached microtubules are regulated by hepatoma-upregulated protein (HURP) and the mitotic kinesin-8 Kif18A, but the underlying mechanism remains elusive. Using single-molecule imaging

Identifiers

PMID38854046
PMCPMC11160874

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.