Evidence map›Paper›PMID 38854027›Full record

ArticlebioRxiv : the preprint server for biology2024

Psilocybin reduces heroin seeking behavior and modulates inflammatory gene expression in the nucleus accumbens and prefrontal cortex of male rats.

Gabriele Floris, Konrad R Dabrowski, Mary Tresa Zanda, Stephanie E Daws

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors.

Gabriele FlorisCenter for Substance Abuse Research, Temple University, Philadelphia, PA USA.
Konrad R DabrowskiCenter for Substance Abuse Research, Temple University, Philadelphia, PA USA.
Mary Tresa ZandaCenter for Substance Abuse Research, Temple University, Philadelphia, PA USA.
Stephanie E DawsCenter for Substance Abuse Research, Temple University, Philadelphia, PA USA.ORCID 0000-0002-4913-8997

Funding

Pilot Projects Core (PPC)P30DA013429 · NIDA · TEMPLE UNIV OF THE COMMONWEALTH · PI Anjali M Rajadhyaksha · 2000 to 2026
$34.6M
TRAINING PROGRAM: DRUGS OF ABUSE RELATED NEUROPEPTIDEST32DA007237 · NIDA · TEMPLE UNIV OF THE COMMONWEALTH · PI ELLEN M UNTERWALD · 1988 to 2026
$10.6M
Circular RNA signaling in opioid seeking phenotypesDP1DA051550 · NIDA · TEMPLE UNIV OF THE COMMONWEALTH · PI DAWS, STEPHANIE · 2020 to 2024
$2.4M
NIDA NIH HHS DP1 DA051550NIDA NIH HHS P30 DA013429NIDA NIH HHS T32 DA007237
6 · The paper itself

Abstract

Preclinical and human studies indicate psilocybin may reduce perseverant maladaptive behaviors, including nicotine and alcohol seeking. Such studies in the opioid field are lacking, though opioids are involved in more >50% of overdose deaths. Psilocybin is an agonist at the serotonin 2A receptor (5-HT

Indexed as

cortexdrug-seekingheroininflammationnucleus accumbensopioidpsilocybinpsychedelicrelapseself-administrationserotonintranscriptome

Identifiers

PMID38854027
PMCPMC11160682

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.