Evidence map›Paper›PMID 38853957›Full record

ArticlebioRxiv : the preprint server for biology2024

Modular, inducible, and titratable expression systems for

Emily E Bacon, Jennifer S Tran, Nischala Nadig, Jason M Peters

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors.

Emily E BaconPharmaceutical Sciences Division, School of Pharmacy, University of Wisconsin-Madison, Madison, WI 53705.ORCID 0000-0001-8090-7689
Jennifer S TranPharmaceutical Sciences Division, School of Pharmacy, University of Wisconsin-Madison, Madison, WI 53705.ORCID 0000-0003-4846-7163
Nischala NadigPharmaceutical Sciences Division, School of Pharmacy, University of Wisconsin-Madison, Madison, WI 53705.ORCID 0000-0002-8610-290X
Jason M PetersPharmaceutical Sciences Division, School of Pharmacy, University of Wisconsin-Madison, Madison, WI 53705.ORCID 0000-0003-2722-8382

Funding

Cross-species Analysis of Bacterial Gene NetworksR35GM150487 · NIGMS · UNIVERSITY OF WISCONSIN-MADISON · PI Jason M. Peters · 2023 to 2026
$1.5M
Special BD LSR FortessaS10OD018202 · OD · UNIVERSITY OF WISCONSIN-MADISON · PI PATANKAR, MANISH S · 2014 to 2014
$351k
CRISPR-based Functional Genomics in Pathogenic BacteriaK22AI137122 · NIAID · UNIVERSITY OF WISCONSIN-MADISON · PI PETERS, JASON M. · 2018 to 2019
$269k
NIAID NIH HHS K22 AI137122NIGMS NIH HHS R35 GM150487NIH HHS S10 OD018202
6 · The paper itself

Abstract

Gene expression systems that transcend species barriers are needed for cross-species analysis of gene function. In particular, expression systems that can be utilized in both model and pathogenic bacteria underpin comparative functional approaches that inform conserved and variable features of bacterial physiology. Here, we develop replicative and integrative vectors alongside a novel, IPTG-inducible promoter that can be used in the model bacterium

Indexed as

cloninggene expressionshuttle vectorsynthetic biologyTn7 vector

Identifiers

PMID38853957
PMCPMC11160707

What OpenQuestion holds

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LicenceCC BY-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.