Evidence map›Paper›PMID 38853555›Full record

ArticlePhilosophical transactions of the Royal Society of London. Series B, Biological sciences2024

Enhanced long-term potentiation in the anterior cingulate cortex of tree shrew.

Qian Song, Xu-Hui Li, Jing-Shan Lu, Qi-Yu Chen, Ren-Hao Liu, Si-Bo Zhou, Min Zhuo

Abstract read
In one paragraph

Article in Philosophical transactions of the Royal Society of London. Series B, Biological sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Adenylyl Cyclases as Therapeutic Targets in Neuroregeneration.International journal of molecular sciences · 2025
    Review
  3. Long-term potentiation: 50 years on: past, present and future.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2024
    Article
  4. Enhanced long-term potentiation in the anterior cingulate cortex of tree shrew.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Qian Song *Center for Neuron and Disease, Frontier Institutes of Science and Technology, Xi'an Jiaotong University , Xi'an 710049, People's Republic of China.ORCID 0009-0003-5426-3041
Xu-Hui Li *Center for Neuron and Disease, Frontier Institutes of Science and Technology, Xi'an Jiaotong University , Xi'an 710049, People's Republic of China.ORCID 0000-0003-4376-6252
Jing-Shan Lu *Center for Neuron and Disease, Frontier Institutes of Science and Technology, Xi'an Jiaotong University , Xi'an 710049, People's Republic of China.ORCID 0000-0002-7330-6567
Qi-Yu ChenCenter for Neuron and Disease, Frontier Institutes of Science and Technology, Xi'an Jiaotong University , Xi'an 710049, People's Republic of China.
Ren-Hao LiuCenter for Neuron and Disease, Frontier Institutes of Science and Technology, Xi'an Jiaotong University , Xi'an 710049, People's Republic of China.
Si-Bo ZhouCenter for Neuron and Disease, Frontier Institutes of Science and Technology, Xi'an Jiaotong University , Xi'an 710049, People's Republic of China.
Min ZhuoCenter for Neuron and Disease, Frontier Institutes of Science and Technology, Xi'an Jiaotong University , Xi'an 710049, People's Republic of China.ORCID 0000-0001-9062-3241

Funding

Canadian Institute for Health Research operating and project GrantsOntario-China Research and Innovation Fund (OCRIF)
6 · The paper itself

Abstract

Synaptic plasticity is a key cellular model for learning, memory and chronic pain. Most previous studies were carried out in rats and mice, and less is known about synaptic plasticity in non-human primates. In the present study, we used integrative experimental approaches to study long-term potentiation (LTP) in the anterior cingulate cortex (ACC) of adult tree shrews. We found that glutamate is the major excitatory transmitter and α-amino-3-hydroxy-5-methyl-4-isoxazole-propionicacid (AMPA) receptors mediate postsynaptic responses. LTP in tree shrews was greater than that in adult mice and lasted for at least 5 h.

Indexed as

Gyrus CinguliLong-Term PotentiationReceptors, AMPAReceptors, N-Methyl-D-AspartateTupaiidaeAdenylyl CyclasesAnimalsGlutamic AcidMaleMiceadenylyl cyclase 1Adenylyl CyclasesGlutamic AcidReceptors, AMPAReceptors, N-Methyl-D-AspartateACCcalcium imagingLTPMED64non-human primatetree shrew

Identifiers

PMID38853555
PMCPMC11343311

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.