Evidence map›Paper›PMID 38853516›Full record

ArticleHuman vaccines & immunotherapeutics2024

Design and evaluation of mRNA encoding recombinant neutralizing antibodies for botulinum neurotoxin type B intoxication prophylaxis.

Gulisaina Qiaerxie, Yujia Jiang, Gege Li, Zhixin Yang, Feng Long, Yunzhou Yu, Jian Sheng Lu, Peng Du, Yong Cui

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Human vaccines & immunotherapeutics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Botulinum neurotoxin: from molecular pathogenesis to emerging countermeasures.Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society · 2026
    Review
  2. Review
  3. Nebulization of an mRNA-encoded monoclonal antibody for passive immunization of foals against Rhodococcus equi.Molecular therapy : the journal of the American Society of Gene Therapy · 2025
    Article
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Gulisaina QiaerxieSchool of Medical Device, Shenyang Pharmaceutical University, Shenyang, Liaoning, China.
Yujia JiangProtein Engineering Laboratory, Beijing Institute of Biotechnology, Beijing, China.
Gege LiSchool of Medical Device, Shenyang Pharmaceutical University, Shenyang, Liaoning, China.
Zhixin YangProtein Engineering Laboratory, Beijing Institute of Biotechnology, Beijing, China.
Feng LongSchool of Medical Device, Shenyang Pharmaceutical University, Shenyang, Liaoning, China.
Yunzhou YuProtein Engineering Laboratory, Beijing Institute of Biotechnology, Beijing, China.
Jian Sheng LuLaboratory of Advanced Biotechnology, Beijing Institute of Biotechnology, Beijing, China.
Peng DuProtein Engineering Laboratory, Beijing Institute of Biotechnology, Beijing, China.
Yong CuiSchool of Medical Device, Shenyang Pharmaceutical University, Shenyang, Liaoning, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Among all natural and synthetic toxins, botulinum neurotoxins (BoNTs), produced by

Indexed as

Antibodies, NeutralizingBotulinum Toxins, Type ABotulismRNA, MessengerAnimalsAntibodies, BacterialFemaleHumansLiposomesMiceMice, Inbred BALB CNanoparticlesVaccines, SyntheticAntibodies, BacterialAntibodies, NeutralizingBotulinum Toxins, Type ALipid NanoparticlesLiposomesrimabotulinumtoxinBRNA, MessengerVaccines, SyntheticBotulinum neurotoxinheavy-chain antibodylipid nanoparticlemRNAprophylaxis

Identifiers

PMID38853516
PMCPMC11168212

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.