Evidence map›Paper›PMID 38853401›Full record

ReviewPest management science2025

Discovery and biological profile of pyridachlometyl.

Yuichi Matsuzaki, Makoto Kurahashi, Satoshi Watanabe, So Kiguchi, Toshiyuki Harada, Fukumatsu Iwahashi

Abstract readReview
In one paragraph

Review in Pest management science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Yuichi MatsuzakiHealth & Crop Sciences Research Laboratory, Sumitomo Chemical Co., Takarazuka, Japan.ORCID https://orcid.org/0000-0002-6486-2721
Makoto KurahashiHealth & Crop Sciences Research Laboratory, Sumitomo Chemical Co., Takarazuka, Japan.
Satoshi WatanabeHealth & Crop Sciences Research Laboratory, Sumitomo Chemical Co., Takarazuka, Japan.
So KiguchiHealth & Crop Sciences Research Laboratory, Sumitomo Chemical Co., Takarazuka, Japan.
Toshiyuki HaradaHealth & Crop Sciences Research Laboratory, Sumitomo Chemical Co., Takarazuka, Japan.
Fukumatsu IwahashiHealth & Crop Sciences Research Laboratory, Sumitomo Chemical Co., Takarazuka, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pyridachlometyl is a novel tubulin dynamics modulator fungicide developed by Sumitomo as a new agent designed to tackle fungicide resistance. Pyridachlometyl is being developed as a first-in-class molecule with an anti-tubulin mode of action, the chemical structure of which is characterized by a unique tetrasubstituted pyridazine ring. The first commercial product 'Fuseki flowable' received initial registration in 2023 in Japan. The concepts of the discovery project, optimization of chemical structures, and biological profiles are reviewed herein. © 2024 The Author(s). Pest Management Science published by John Wiley & Sons Ltd on behalf of Society of Chemical Industry.

Indexed as

Fungicides, IndustrialPyridazinesTubulin ModulatorsAnimalsDrug DiscoveryFungicides, IndustrialPyridazinesTubulin Modulatorsbioisosterefungicide resistancepyridachlometylpyridazinetubulin

Identifiers

PMID38853401
PMCPMC11981980

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.