Evidence map›Paper›PMID 38851819›Full record

ArticleCommunications chemistry2024

NIR light-activated nanocomposites combat biofilm formation and enhance antibacterial efficacy for improved wound healing.

Irfan Ullah, Shahin Shah Khan, Waqar Ahmad, Luo Liu, Ahmed Rady, Badr Aldahmash, Yingjie Yu, Jian Wang, Yushu Wang

Abstract read
In one paragraph

Article in Communications chemistry, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Irfan Ullah *College of Life Science and Technology, Beijing University of Chemical Technology, No. 15 East Road of North Third Ring Road, Chao Yang District, Beijing, 100029, China.
Shahin Shah Khan *College of Life Science and Technology, Beijing University of Chemical Technology, No. 15 East Road of North Third Ring Road, Chao Yang District, Beijing, 100029, China.
Waqar AhmadCollege of Life Science and Technology, Beijing University of Chemical Technology, No. 15 East Road of North Third Ring Road, Chao Yang District, Beijing, 100029, China.
Luo LiuCollege of Life Science and Technology, Beijing University of Chemical Technology, No. 15 East Road of North Third Ring Road, Chao Yang District, Beijing, 100029, China.
Ahmed RadyDepartment of Zoology, College of Science, King Saud University, P.O. Box 2455, Riyadh, 11451, Saudi Arabia.
Badr AldahmashDepartment of Zoology, College of Science, King Saud University, P.O. Box 2455, Riyadh, 11451, Saudi Arabia.
Yingjie YuState Key Laboratory of Organic-Inorganic Composites, Beijing University of Chemical Technology, No. 15 East Road of North Third Ring Road, Chao Yang District, Beijing, 100029, China. yuyingjie@mail.buct.edu.cn.ORCID http://orcid.org/0000-0002-2543-9808
Jian WangDepartment of Head and Neck Surgery, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100021, China. wangjianpumc@126.com.ORCID http://orcid.org/0000-0003-2729-5550
Yushu WangThe People's Hospital of Gaozhou, National Drug Clinical Trial Institution, Gaozhou City, 525200, China. wysmjeda@gmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Nanoparticle-based therapies are emerging as a pivotal frontier in biomedical research, showing their potential in combating infections and facilitating wound recovery. Herein, selenium-tellurium dopped copper oxide nanoparticles (SeTe-CuO NPs) with dual photodynamic and photothermal properties were synthesized, presenting an efficient strategy for combating bacterial infections. In vitro evaluations revealed robust antibacterial activity of SeTe-CuO NPs, achieving up to 99% eradication of bacteria and significant biofilm inhibition upon near-infrared (NIR) irradiation. Moreover, in vivo studies demonstrated accelerated wound closure upon treatment with NIR-activated SeTe-CuO NPs, demonstrating their efficacy in promoting wound healing. Furthermore, SeTe-CuO NPs exhibited rapid bacterial clearance within wounds, offering a promising solution for wound care. Overall, this versatile platform holds great promise for combating multidrug-resistant bacteria and advancing therapeutic interventions in wound management.

Identifiers

PMID38851819
PMCPMC11162491

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.