Evidence map›Paper›PMID 38851706›Full record

Trial reportBMC public health2024

The association between HIV infection, disability and lifestyle activity among middle-aged and older adults: an analytical cross-sectional study in Ivory Coast (the VIRAGE study).

Pierre Debeaudrap, Nadine Etoundi, Joseph Tegbe, Nelly Assoumou, Zelica Dialo, Aristophane Tanon, Charlotte Bernard, Fabrice Bonnet, Hortense Aka, Patrick Coffie

Registry-linked trialAbstract readClinical Trial
In one paragraph

Trial report in BMC public health, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05199831 (Preliminary Situational Analysis of a Pilot Rehabilitation Intervention Based on Physical Exercise for People Living With HIV in Ivory Coast), which is not on this map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05199831 completednot on this map

Preliminary Situational Analysis of a Pilot Rehabilitation Intervention Based on Physical Exercise for People Living With HIV in Ivory Coast

TypeobservationalSponsorProgramme PAC-CI, Site ANRS-MIE de Côte d'IvoireRan2021 to 2022Enrolled500ConditionsHIV Infections
3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Challenges to Physical Activity Participation Among Older People Living with HIV: Scoping Review.International journal of environmental research and public health · 2025
    Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Pierre DebeaudrapCentre Population and Development (Ceped), French National Research Institute for Sustainable Development (IRD) and Paris University, Inserm ERL 1244, 45 Rue Des Saints Pères, 75006, Paris, France. pierre.debeaudrap@ird.fr.
Nadine EtoundiInfectious and Tropical Diseases Service (SMIT), Treichville Teaching Hospital, Abidjan, Côte d'Ivoire.
Joseph TegbeProgramme PAC-CI, Treichville Teaching Hospital, Abidjan, Côte d'Ivoire.
Nelly AssoumouProgramme PAC-CI, Treichville Teaching Hospital, Abidjan, Côte d'Ivoire.
Zelica DialoInfectious and Tropical Diseases Service (SMIT), Treichville Teaching Hospital, Abidjan, Côte d'Ivoire.
Aristophane TanonInfectious and Tropical Diseases Service (SMIT), Treichville Teaching Hospital, Abidjan, Côte d'Ivoire.
Charlotte BernardUniversity of Bordeaux, National Institute for Health and Medical Research (INSERM) UMR 1219, Research Institute for Sustainable Development (IRD) EMR 271, Bordeaux Population Health Centre, Bordeaux, France.
Fabrice BonnetUniversity of Bordeaux, National Institute for Health and Medical Research (INSERM) UMR 1219, Research Institute for Sustainable Development (IRD) EMR 271, Bordeaux Population Health Centre, Bordeaux, France.
Hortense AkaDepartment of Psychology, Felix Houphouet Boigny University, Abidjan, Côte d'Ivoire, Ivory Coast.
Patrick CoffieProgramme PAC-CI, Treichville Teaching Hospital, Abidjan, Côte d'Ivoire.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionPeople living with HIV (PLWH) live longer and face new health challenges resulting from the confluence of chronic HIV infection and the natural effect of aging and comorbidities. However, there is a dearth of information on the long-term impact of HIV infection on the health and wellbeing of PLWH in sub-Saharan Africa. This research aimed to fill this gap by reporting on physical, functional and social outcomes among PLWH treated at a referral center in Abidjan, Ivory Coast, and comparing them with those of a control group.

methodsBody composition, functional capacity, sarcopenia, limitations in daily activities and social participation were assessed among 300 PLWH (aged ≥ 30 years) and 200 uninfected adults of similar age and sex. The associations between these outcomes and participants' socioeconomic characteristics, HIV history and physical activity level were assessed using generalized additive models adjusted for age and sex.

resultsThe median age was 51 years, and the median antiretroviral therapy duration was 15 years. Compared to controls, PLWH reported higher levels of physical activity (p < 0.0001). They had a lower muscle index (adjusted p < 0.0001) and grip strength (adjusted p < 0.0001) but achieved similar performance on the 6-min walk test (6MWT, p = 0.2). Among PLWH, physical activity level was positively associated with better performance in the 6MWT (p = 0.006) and greater hand grip strength (p = 0.04). The difference in physical performance according to the level of physical activity appeared mainly after the age of 60. PLWH reported similar rates of activity limitations (p = 0.8), lower depression levels and greater scores for social functioning (p = 0.02).

conclusionIn this study, PLWH achieved high levels of physical activity, which may explain why they maintained good physical performance and social functioning despite having a higher risk of sarcopenia. These results have important implications for resource-limited health systems and show avenues for chronic care models.

trial registrationThis study was registered on the ClinicalTrials.gov website (NCT05199831, first registration the 20/01/2022).

Indexed as

ExerciseHIV InfectionsActivities of Daily LivingAdultAgedBody CompositionCote d'IvoireCross-Sectional StudiesFemaleHumansLife StyleMaleMiddle AgedPersons with DisabilitiesSarcopeniaSocial ParticipationAgingDisabilityHIVPhysical activity

Identifiers

PMID38851706
PMCPMC11161960

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.