Trial reportJournal of neuroengineering and rehabilitation2024
Exoskeleton rehabilitation robot training for balance and lower limb function in sub-acute stroke patients: a pilot, randomized controlled trial.
Trial report in Journal of neuroengineering and rehabilitation, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 6 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
24 citing papers in PubMed, 6 syntheses or guidelines pooled it.
- Effectiveness of non-pharmacological interventions for lower limb motor impairment in post-stroke hemiplegia: a systematic review and Bayesian network meta-analysis.Journal of neuroengineering and rehabilitation · 2026Pooled it
- Post-stroke lower limb rehabilitation: a comparative study between exoskeleton robots and traditional gait training.Journal of neuroengineering and rehabilitation · 2026Pooled it
- Effects of BCI-based lower limb robots on lower limb function and cognition in stroke patients: a preliminary systematic review.Frontiers in human neuroscience · 2026Pooled it
- Bibliometric analysis of surface electromyography trends in stroke rehabilitation research.Frontiers in neurology · 2025Pooled it
- Systematic review and meta-analysis of effectiveness of robotic therapy in the recovery of motor functions after stroke.Frontiers in human neuroscience · 2025Pooled it
- Efficacy of acupuncture combined with mirror therapy in the treatment of post-stroke limb movement disorders: a systematic review and meta-analysis of randomised controlled trials.Frontiers in rehabilitation sciences · 2024Pooled it
- The effect of high-intensity interval training on cardiorespiratory fitness for non-ambulatory stroke survivors: a randomized controlled trial.Frontiers in sports and active living · 2026Trial
- Unilateral Exoskeleton Training for Balance/Gait in Hemiplegic Stroke: Pilot Study.Behavioural neurology · 2026Trial
- Effect of robot-assisted gait training combined with electroacupuncture on lower limb motor function and brain network characteristics in stroke: an EEG study.Journal of neuroengineering and rehabilitation · 2025Trial
- Enhanced motor recovery in stroke patients through dual-modal intervention: motor imagery and task-oriented robot training.Journal of neuroengineering and rehabilitation · 2025Trial
- Trial
- Interim results of exoskeletal wearable robot for gait recovery in subacute stroke patients.Scientific reports · 2025Trial
- Article
- Review
- Optimal exercise modalities for enhancing motor function recovery after stroke: a Bayesian systematic review with pairwise and network meta-analyses.EClinicalMedicine · 2026Article
- The Effects of Clinical Applications of Robot-Assisted Therapy Methods: End-Effector, Fixed Exoskeleton, and Wearable Exoskeleton on Functional Activities in Stroke Patients.Life (Basel, Switzerland) · 2026Article
- Priming iTBS for lower limb rehabilitation after stroke: Protocol for a randomized controlled trial on efficacy and neuroplasticity.PloS one · 2026Article
- Effects of exercise regimens on balance ability in older patients with osteoporosis: a systematic review and Bayesian network meta-analysis of randomized controlled trials.Frontiers in physiology · 2026Review
- A novel scheme for speed variation of a robotic cane to improve step length symmetry during overground walking.Scientific reports · 2025Article
- Applications of Robotic Exoskeletons as Motion-Assistive Systems in Cancer Rehabilitation.Research (Washington, D.C.) · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
17 authors.
Funding
Abstract
purposeThis pilot study aimed to investigate the effects of REX exoskeleton rehabilitation robot training on the balance and lower limb function in patients with sub-acute stroke.
methodsThis was a pilot, single-blind, randomized controlled trial. Twenty-four patients with sub-acute stroke (with the course of disease ranging from 3 weeks to 3 months) were randomized into two groups, including a robot group and a control group. Patients in control group received upright bed rehabilitation (n = 12) and those in robot group received exoskeleton rehabilitation robot training (n = 12). The frequency of training in both groups was once a day (60 min each) for 5 days a week for a total of 4 weeks. Besides, the two groups were evaluated before, 2 weeks after and 4 weeks after the intervention, respectively. The primary assessment index was the Berg Balance Scale (BBS), whereas the secondary assessment indexes included the Fugl-Meyer Lower Extremity Motor Function Scale (FMA-LE), the Posture Assessment Scale for Stroke Patients (PASS), the Activities of Daily Living Scale (Modified Barthel Index, MBI), the Tecnobody Balance Tester, and lower extremity muscle surface electromyography (sEMG).
resultsThe robot group showed significant improvements (P < 0.05) in the primary efficacy index BBS, as well as the secondary efficacy indexes PASS, FMA-LE, MBI, Tecnobody Balance Tester, and sEMG of the lower limb muscles. Besides, there were a significant differences in BBS, PASS, static eye-opening area or dynamic stability limit evaluation indexes between the robotic and control groups (P < 0.05).
conclusionsThis is the first study to investigate the effectiveness of the REX exoskeleton rehabilitation robot in the rehabilitation of patients with stroke. According to our results, the REX exoskeleton rehabilitation robot demonstrated superior potential efficacy in promoting the early recovery of balance and motor functions in patients with sub-acute stroke. Future large-scale randomized controlled studies and follow-up assessments are needed to validate the current findings. CLINICAL TRIALS REGISTRATION: URL: https://www.chictr.org.cn/index.html.Unique identifier: ChiCTR2300068398.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.