Evidence map›Paper›PMID 38850492›Full record

SynthesisCurrent pain and headache reports2024

The Role of Platelet Rich Plasma in Vertebrogenic and Discogenic Pain: A Systematic Review and Meta-Analysis.

Saurabh Kataria, Jeremiah Hilkiah Wijaya, Utsav Patel, Kevin Yabut, Tawfiq Turjman, Muhammad Abubakar Ayub, Nihar Upadhyay, Moinulhaq Makrani, Hisham Turjman, Ahmed Mostafa Abdalla Mohamed and 1 more

Erratum issuedAbstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in Current pain and headache reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Review
  4. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors.

Saurabh KatariaDepartment of Neurology, Louisiana State University Health Sciences Center at Shreveport, 1501 Kings Highway, Shreveport, LA, 71103, USA. saurabh.kataria@lsuhs.edu.ORCID http://orcid.org/0000-0001-8104-3085
Jeremiah Hilkiah WijayaDepartment of Neurosurgery, Siloam Hospital Lippo Village, Tangerang, Banten, Indonesia.ORCID http://orcid.org/0000-0001-8771-2163
Utsav PatelMayo Clinic, Jacksonville, FL, 32224, USA.ORCID http://orcid.org/0009-0009-0631-3570
Kevin YabutLouisiana State University Health Sciences Center, Shreveport, LA, 71103, USA.
Tawfiq TurjmanSchool of Medicine, Royal College of Surgeons in Ireland, Baharain, USA.ORCID http://orcid.org/0000-0001-7609-7337
Muhammad Abubakar AyubDepartment of Neurology, Louisiana State University Health Sciences Center at Shreveport, 1501 Kings Highway, Shreveport, LA, 71103, USA.ORCID http://orcid.org/0000-0003-3336-0574
Nihar UpadhyayDepartment of Internal Medicine, GMERS Medical College, Gotri, Vadodara, Gujarat, 390021, India.
Moinulhaq MakraniDept. of Pharmacology, Parul Institute of Medical Science and Research, Waghodiya, Gujarat, 291760, India.
Hisham TurjmanSchool of Medicine, Royal College of Surgeons in Ireland, Baharain, USA.ORCID http://orcid.org/0009-0009-7893-1909
Ahmed Mostafa Abdalla MohamedSchool of Medicine, Royal College of Surgeons in Ireland, Baharain, USA.ORCID http://orcid.org/0009-0009-2363-5926
Alan D KayeDepartment of Anaesthesiology and Interventional Pain, Louisiana State University Health Sciences Center at Shreveport, Shreveport, LA, 71103, USA.ORCID http://orcid.org/0000-0003-2464-0187

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purpose of reviewThe present investigation evaluates clinical uses and roles of platelet rich plasma in the management of vetrebrogenic and discogenic mediated pain states. RECENT

findingsBack pain is a common and significant condition that affects millions of people around the world. The cause of back pain is often complex and multifactorial, with discogenic and vertebrogenic pain being two subtypes of back pain. Currently, there are numerous methods and modalities in which back pain is managed and treated such as physical therapy, electrical nerve stimulation, pharmacotherapies, and platelet-rich plasma. To conduct this systematic review, the authors used the keywords "platelet-rich plasma", "vertebrogenic pain", and "discogenic pain", on PubMed, EuroPMC, Who ICTRP, and clinicaltrials.gov to better elucidate the role of this treatment method for combating vertebrogenic and discogenic back pain. In recent decades, there has been a rise in popularity of the use of platelet-rich plasma for the treatment of numerous musculoskeletal conditions. Related to high concentration of platelets, growth factors, cytokines, and chemokines, platelet-rich plasma is effective in reducing pain related symptoms and in the treatment of back pain. Platelet-rich plasma use has evolved and gained popularity for pain related conditions, including vertebrogenic and discogenic back pain. Additional well-designed studies are warranted in the future to better determine best practice strategies to provide future clinicians with a solid foundation of evidence to make advancements with regenerative medical therapies such as platelet-rich plasma.

Indexed as

Back PainPlatelet-Rich PlasmaHumansBack painDiscogenic painLow back painPlatelet-rich plasmaVertebrogenic pain

Identifiers

PMID38850492
PMCPMC11272713

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.