Evidence map›Paper›PMID 38850453›Full record

ArticleDaru : journal of Faculty of Pharmacy, Tehran University of Medical Sciences2024

Effect of the treatment of iron deficiency anemia on chronic drug-resistant cough: a rare case report.

Fatemeh Akbari, Lale Vahedi Larijani, Ehsan Rajabi Visroodi, Bahareh Hakiminia

Abstract readCase Reports
In one paragraph

Article in Daru : journal of Faculty of Pharmacy, Tehran University of Medical Sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Fatemeh AkbariDepartment of Pharmacognosy, School of Pharmacy, Semnan University of Medical Sciences, Semnan, Iran.ORCID http://orcid.org/0000-0002-7879-3667
Lale Vahedi LarijaniDepartment of Pathology, School of Medicine, Mazandaran University of Medical Sciences, Sari, Iran.ORCID http://orcid.org/0000-0003-3277-0176
Ehsan Rajabi VisroodiDepartment of Pharmaceutics, School of Pharmacy, Mazandaran University of Medical Sciences, Sari, Iran.ORCID http://orcid.org/0000-0001-5931-1426
Bahareh HakiminiaDepartment of Clinical Pharmacy, School of Pharmacy, Semnan University of Medical Sciences, Semnan, Iran. baharehhakiminia@yahoo.com.ORCID http://orcid.org/0000-0003-2669-2837

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundA persistent difficult-to-treat cough can be exhausting. Iron is an essential element that plays an important role in regulating the production of pro-inflammatory cytokines, and its deficiency may potentiate airway inflammation and dysfunction. There is a paucity of data regarding a link between iron deficiency (ID) and idiopathic cough.

objectivesIn this study, a case of persistent non-productive cough, which was unresponsive to targeted treatment approaches but responsive to iron therapy, is reported.

methodsA 53-year-old woman came to a medical clinic with complaints of a chronic and progressive non-productive cough. She underwent a complete clinical and paraclinical evaluation.

resultsHer vital signs were stable and no abnormalities were found on the physical examination. The results of the spirometry and chest radiography were unremarkable. The laboratory test indicated hypochromic microcytic anemia, with a hemoglobin value of 9.6 g/dL. Her cough was resolved after treatment of iron-deficiency anemia with an oral nutraceutical capsule containing 28 mg of elemental iron (as ferrous bis-glycinate) plus folic acid, vitamin B12, and vitamin C, once daily for six months.

conclusionIn the case of unexplained chronic cough, resistant to targeted therapies, investigation and treatment of ID may contribute to the resolution of cough.

Indexed as

Anemia, Iron-DeficiencyCoughDrug ResistanceAscorbic AcidChronic DiseaseDietary SupplementsFemaleFerrous CompoundsFolic AcidHumansIronMiddle AgedTreatment OutcomeVitamin B 12Ascorbic AcidFerrous CompoundsFolic AcidIronVitamin B 12CoughDrug resistanceIron deficiencyTherapy

Identifiers

PMID38850453
PMCPMC11554957

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.