Evidence map›Paper›PMID 38850376›Full record

ArticleBiochemical genetics2025

Genetic Variability of CYP4F2, CYP2D6, CYP2E1, and ACE in the Chinese Yi Population.

Jinping Guo, Wenqian Zhou, Xiaoya Ma, Yujie Li, Huan Zhang, Jie Wei, Shuli Du, Tianbo Jin

Abstract read
PubMed Publisher
In one paragraph

Article in Biochemical genetics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Jinping GuoKey Laboratory of Resource Biology and Biotechnology in Western China (Northwest University), School of Life Sciences, Ministry of Education, Northwest University, #229 North TaiBai Road, Xi'an, Shaanxi, 710069, China.
Wenqian ZhouKey Laboratory of Resource Biology and Biotechnology in Western China (Northwest University), School of Life Sciences, Ministry of Education, Northwest University, #229 North TaiBai Road, Xi'an, Shaanxi, 710069, China.
Xiaoya MaKey Laboratory of Resource Biology and Biotechnology in Western China (Northwest University), School of Life Sciences, Ministry of Education, Northwest University, #229 North TaiBai Road, Xi'an, Shaanxi, 710069, China.
Yujie LiKey Laboratory of Resource Biology and Biotechnology in Western China (Northwest University), School of Life Sciences, Ministry of Education, Northwest University, #229 North TaiBai Road, Xi'an, Shaanxi, 710069, China.
Huan ZhangKey Laboratory of Resource Biology and Biotechnology in Western China (Northwest University), School of Life Sciences, Ministry of Education, Northwest University, #229 North TaiBai Road, Xi'an, Shaanxi, 710069, China.
Jie WeiKey Laboratory of Resource Biology and Biotechnology in Western China (Northwest University), School of Life Sciences, Ministry of Education, Northwest University, #229 North TaiBai Road, Xi'an, Shaanxi, 710069, China.
Shuli DuKey Laboratory of Resource Biology and Biotechnology in Western China (Northwest University), School of Life Sciences, Ministry of Education, Northwest University, #229 North TaiBai Road, Xi'an, Shaanxi, 710069, China. 786209865@qq.comm.
Tianbo JinKey Laboratory of Resource Biology and Biotechnology in Western China (Northwest University), School of Life Sciences, Ministry of Education, Northwest University, #229 North TaiBai Road, Xi'an, Shaanxi, 710069, China. jintb@nwu.edu.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Genetic polymorphisms of very important pharmacogenes (VIP) are a significant factor contributing to inter-individual variability in drug therapy. The purpose of this study was to identify significantly different loci in the Yi population and to enrich their pharmacogenomic information. 54 VIP variants were selected from the Pharmacogenomics Knowledge Base (PharmGKB) and genotyped in 200 Yi individuals. Then, we compared their genotype distribution between the Yi population and the other 26 populations using the χ

Indexed as

Cytochrome P-450 CYP2D6Cytochrome P-450 CYP2E1Cytochrome P450 Family 4Peptidyl-Dipeptidase APolymorphism, Single NucleotideChinaEast Asian PeopleFemaleGene FrequencyGenotypeHumansMaleACE protein, humanCYP4F2 protein, humanCytochrome P-450 CYP2D6Cytochrome P-450 CYP2E1Cytochrome P450 Family 4Peptidyl-Dipeptidase AGenetic polymorphismsPharmacogenomicsThe Yi populationVIP variants

Identifiers

PMID38850376

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.