Evidence map›Paper›PMID 38850356›Full record

ArticleInternal and emergency medicine2024

Rifaximin in diverticulosis and diverticular disease: a national survey among Italian gastroenterologists and general practitioners.

Luigi Gatta, Massimo Bellini, Carmelo Scarpignato, Walter Marrocco, Alberto Chiriatti, Antonio Grosso, Christian Lambiase, Paolo Usai-Satta, Roberto Vassallo, Pierluigi Bartoletti and 5 more

Abstract read
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In one paragraph

Article in Internal and emergency medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Luigi GattaGastroenterology Unit, ASL Toscana Nord-Ovest, Versilia Hospital, 55041, Lido di Camaiore, Italy. gattalg@gmail.com.ORCID 0000-0001-5789-3813
Massimo BelliniGastrointestinal Unit, Department of Translational Sciences and New Technologies in Medicine and Surgery, University of Pisa, Pisa, Italy.
Carmelo ScarpignatoDepartment of Health Sciences, United Campus of Malta, Msida, Malta.ORCID 0000-0001-5645-857X
Walter MarroccoPrimary Care Physician Azienda Sanitaria Locale (ASL), Roma 5, Tivoli, Rome, Italy.
Alberto ChiriattiPrimary Care Physician Azienda Sanitaria Locale (ASL), Roma 3, Rome, Italy.
Antonio GrossoGastrointestinal Unit, Department of Translational Sciences and New Technologies in Medicine and Surgery, University of Pisa, Pisa, Italy.
Christian LambiaseGastrointestinal Unit, Department of Translational Sciences and New Technologies in Medicine and Surgery, University of Pisa, Pisa, Italy.
Paolo Usai-SattaGastroenterology Unit, Brotzu Hospital, Cagliari, Italy.
Roberto VassalloGastroenterology and Endoscopy Unit, Buccheri la Ferla Hospital, Palermo, Italy.
Pierluigi BartolettiPrimary Care Physician Azienda Sanitaria Locale (ASL), Roma 2, Rome, Italy.
Fabio MonicaGastroenterology and Digestive Endoscopy Unit, Academic Hospital Cattinara, Trieste, Italy.
Raffaele MantaDigestive Endoscopy Unit, ASL Toscana Nord-Ovest, "Spedali Riuniti" Hospital, Livorno, Italy.
Silvestro ScottiPrimary Care Physician Azienda Sanitaria Locale (ASL), Napoli 1, Naples, Italy.
Marco SonciniDepartment of Internal Medicine, "A. Manzoni" Hospital, Lecco, Italy.
Italian Association of Hospital Gastroenterologists and Endoscopists (AIGO) and the Italian Federation of General Practitioners (FIMMG)

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The management of patients with diverticular disease remains challenging. The aim of this national survey was to assess how gastroenterologists and general practitioners use rifaximin to manage diverticulosis and diverticular disease. Members of the Italian Association of Hospital Gastroenterologists and Endoscopists (AIGO) and the Italian Federation of General Practitioners (FIMMG) were invited to complete a 39-item online survey concerning the use of rifaximin in five clinical settings: (1) diverticulosis; (2) reducing symptoms in symptomatic uncomplicated diverticular disease; (3) reducing the occurrence of diverticulitis in patients with symptomatic uncomplicated diverticular disease (primary prevention); (4) reducing the recurrence of diverticulitis in patients with previous attacks of diverticulitis (secondary prevention); (5) treatment of uncomplicated acute diverticulitis. A total of 1094 physicians completed the survey. Overall, 25.1%, 83.5%, 68%, 74.2%, and 63% of physicians prescribed rifaximin for the clinical settings 1, 2, 3, 4, and 5, respectively. In each clinical setting, the dosage of rifaximin most frequently used was 800 mg/day, the most common duration of therapy was 7 days, and the cyclic administration of treatment (expressed in months) most frequently used was > 24 months. These results highlight that a reappraisal of the use of rifaximin in patients with diverticulosis and diverticular disease is required to reduce the gap between the evidence available and the daily clinical practice, optimizing also the use of healthcare resources.

Indexed as

Diverticular DiseasesGastroenterologistsGeneral PractitionersRifaximinDiverticulumFemaleHumansItalyMaleMiddle AgedPractice Patterns, Physicians'RifamycinsSurveys and QuestionnairesRifamycinsRifaximinAntibioticDiverticular diseaseDiverticulitisDiverticulosisRifaximinSymptomatic uncomplicated diverticular disease (SUDD)Treatment

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Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.