Evidence map›Paper›PMID 38850341›Full record

GuidelineSupportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer2024

Less restrictions in daily life: a clinical practice guideline for children with cancer.

Debbie C Stavleu, Renée L Mulder, Demi M Kruimer, Leontien C M Kremer, Wim J E Tissing, Erik A H Loeffen, social restrictions guideline panel

Abstract readPractice GuidelineSystematic Review
In one paragraph

Guideline in Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Debbie C StavleuUniversity Medical Center Groningen, Beatrix Children's Hospital, Department of Pediatric Oncology/Hematology, University of Groningen, Groningen, The Netherlands.
Renée L MulderPrincess Máxima Center for Pediatric Oncology, Utrecht, The Netherlands.
Demi M KruimerPrincess Máxima Center for Pediatric Oncology, Utrecht, The Netherlands.
Leontien C M KremerPrincess Máxima Center for Pediatric Oncology, Utrecht, The Netherlands.
Wim J E TissingUniversity Medical Center Groningen, Beatrix Children's Hospital, Department of Pediatric Oncology/Hematology, University of Groningen, Groningen, The Netherlands.
Erik A H LoeffenUniversity Medical Center Groningen, Beatrix Children's Hospital, Department of Pediatric Oncology/Hematology, University of Groningen, Groningen, The Netherlands. eah.loeffen@umcg.nl.
social restrictions guideline panel

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeIn current clinical practice, recommendations regarding restrictions in daily life for children with cancer are often lacking or not evidence-based. Critically reviewing the evidence and formulating recommendations are therefore of great importance as social restrictions (e.g., swimming, school attendance, sports) can impair the quality of life of these children severely. Therefore, our aim was to develop a clinical practice guideline for clinicians, children, and their parents regarding social restrictions in children with cancer.

methodsA comprehensive multidisciplinary panel was assembled, comprising 21 professionals and patient representatives. A systematic literature review was performed, including dual appraisal of all citations. The GRADE methodology was used to extract, summarize, and assess the evidence. Multiple in-person meetings were held to rank outcomes, discuss evidence, complete evidence-to-decision frameworks, and formulate recommendations. Final recommendations were unanimously supported by all panel members.

resultsSix studies, including 758 children, formed the evidence base for the recommendations. Given the scarcity of the available evidence and various designs of studies in children with cancer, additional evidence was extracted from adult oncology guidelines, and shared expert opinions were utilized. In total, 14 recommendations were formulated of which multiple result in changes in current policy and standard of practice in the Netherlands. Topics covered in this guideline are swimming, having pets, visiting the zoo or farm, performing sports or high-velocity events, attending school or kindergarten, and use of public transport. This guideline is not intended to provide recommendations for patients after end of treatment, for palliative care settings, or for children undergoing a stem cell transplantation.

conclusionsIn this clinical practice guideline, we provide recommendations regarding restrictions in daily life in children with cancer. These include evidence-based recommendations and, in the absence of sufficient evidence, recommendations based on expert evidence. With these recommendations, we provide guidance for clinicians, children, and parents and contribute to improving quality of life for children with cancer.

Indexed as

NeoplasmsQuality of LifeActivities of Daily LivingChildHumansNetherlandsClinical practice guidelinePediatric oncologySocial restrictions

Identifiers

PMID38850341
PMCPMC11162397

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.