Evidence map›Paper›PMID 38850160›Full record

ArticleNucleic acids research2024

CAbiNet: joint clustering and visualization of cells and genes for single-cell transcriptomics.

Yan Zhao, Clemens Kohl, Daniel Rosebrock, Qinan Hu, Yuhui Hu, Martin Vingron

Abstract read
In one paragraph

Article in Nucleic acids research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Yan ZhaoDepartment of Computational Molecular Biology, Max Planck Institute for Molecular Genetics, Ihnestraße 63-73, 14195 Berlin, Germany.ORCID 0000-0002-3087-4767
Clemens KohlDepartment of Computational Molecular Biology, Max Planck Institute for Molecular Genetics, Ihnestraße 63-73, 14195 Berlin, Germany.ORCID 0000-0002-8614-8940
Daniel RosebrockDepartment of Computational Molecular Biology, Max Planck Institute for Molecular Genetics, Ihnestraße 63-73, 14195 Berlin, Germany.ORCID 0000-0002-4818-4983
Qinan HuDepartment of Pharmacology, School of Medicine, Southern University of Science and Technology, 1088 Xueyuan Avenue, Shenzhen 518055, Guangdong, P.R. China.ORCID 0000-0003-3653-3004
Yuhui HuDepartment of Pharmacology, School of Medicine, Southern University of Science and Technology, 1088 Xueyuan Avenue, Shenzhen 518055, Guangdong, P.R. China.ORCID 0000-0002-5210-5301
Martin VingronDepartment of Computational Molecular Biology, Max Planck Institute for Molecular Genetics, Ihnestraße 63-73, 14195 Berlin, Germany.ORCID 0000-0002-1765-4241

Funding

IMPRSMax Planck SocietyNational Natural Science Foundation of China 82373975Shenzhen Key Laboratory of Gene Regulation and Systems Biology ZDSYS 20200811144002008Shenzhen Science and Technology Program KQTD 20180411143432337Simons Institute for Theory of Computing
6 · The paper itself

Abstract

A fundamental analysis task for single-cell transcriptomics data is clustering with subsequent visualization of cell clusters. The genes responsible for the clustering are only inferred in a subsequent step. Clustering cells and genes together would be the remit of biclustering algorithms, which are often bogged down by the size of single-cell data. Here we present 'Correspondence Analysis based Biclustering on Networks' (CAbiNet) for joint clustering and visualization of single-cell RNA-sequencing data. CAbiNet performs efficient co-clustering of cells and their respective marker genes and jointly visualizes the biclusters in a non-linear embedding for easy and interactive visual exploration of the data.

Indexed as

AlgorithmsGene Expression ProfilingSingle-Cell AnalysisSoftwareTranscriptomeCluster AnalysisHumansSequence Analysis, RNA

Identifiers

PMID38850160
PMCPMC11260446

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.