Evidence map›Paper›PMID 38850073›Full record

ArticleHead & neck2024

Parotidectomy for deep lobe pleomorphic adenomas is associated with higher rates of complications and recurrence.

Helena Levyn, Tejas Subramanian, Alana Eagan, Nora Katabi, Johanna Goldberg, Daniel W Scholfield, Giovanna L Caxeiro, Richard J Wong, Marc A Cohen, Jatin P Shah and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Head & neck, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Helena LevynDepartment of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York, USA.ORCID 0009-0005-4402-6186
Tejas SubramanianWeill Cornell Medicine, New York, New York, USA.ORCID 0000-0003-0323-6716
Alana EaganDepartment of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York, USA.
Nora KatabiDepartment of Pathology, Memorial Sloan Kettering Cancer Center, New York, New York, USA.
Johanna GoldbergLibrary, Memorial Sloan Kettering Cancer Center, New York, New York, USA.
Daniel W ScholfieldDepartment of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York, USA.
Giovanna L CaxeiroDepartment of Radiology, Sloan Kettering Institute, New York, New York, USA.
Richard J WongDepartment of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York, USA.
Marc A CohenDepartment of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York, USA.ORCID 0000-0002-6104-7967
Jatin P ShahDepartment of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York, USA.ORCID 0000-0002-6444-6592
Snehal G PatelDepartment of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York, USA.
Ian GanlyDepartment of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York, USA.ORCID 0000-0001-7636-5426

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Nicholas D Socci · 1985 to 2026
$347.4M
Department of Health and Human Services, National Institutes of Health/NCI Cancer Center P30CA008748NCI NIH HHS P30 CA008748The Michael Wynn research fund
6 · The paper itself

Abstract

backgroundPleomorphic adenoma (PA) is a common parotid tumor, yet due to the relative rarity of deep lobe PA (DLPA), there is a paucity of information about its clinical presentation and surgical outcomes.

methodsWe reviewed the charts of patients with previously untreated parotid PA between the years 1990 and 2015. Clinical parameters and surgical outcomes were compared between superficial lobe PA (SLPA) and DLPA.

resultsThe cohort comprised 147 cases of DLPA and 222 cases of SLPA. DLPA were larger (median 2.6 cm vs. 2.0 cm, p < 0.001), more often discovered incidentally on imaging (33%, n = 48) and had unique presentations (pharyngeal mass, dysphagia, otalgia). Postsurgical complications were more frequently observed in DLPA (41% vs. 30% in SLPA, p = 0.025), mainly transient facial nerve weakness. DLPA also showed higher recurrence rates (n = 6, 4.1% vs. n = 1, 0.4%, p = 0.016).

conclusionsParotidectomy for DLPA carries a higher risk of complications and recurrence compared to SLPA.

Indexed as

Adenoma, PleomorphicNeoplasm Recurrence, LocalParotid NeoplasmsPostoperative ComplicationsAdolescentAdultAgedAged, 80 and overCohort StudiesFemaleHumansMaleMiddle AgedParotid GlandRetrospective StudiesTreatment Outcomebenign mixed tumormajor salivary glandsparapharyngeal spacesurgerysymptoms

Identifiers

PMID38850073
PMCPMC11473235

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.