Evidence map›Paper›PMID 38850040›Full record

Observational studyJournal of intensive care medicine2024

Independent Risk Factors for Prolonged Tube Feeding After Endotracheal Intubation and Ventilation.

Prajwal M Pradhan, Schelomo Marmor, Christopher Tignanelli, Stephanie Misono, Jesse Hoffmeister

Abstract readObservational Study
PubMed Full text at PMC Publisher
In one paragraph

Observational study in Journal of intensive care medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Prajwal M PradhanInstitute of Health Informatics, University of Minnesota, Minneapolis, USA.
Schelomo MarmorCenter for Quality Outcomes, Discovery and Evaluation, University of Minnesota, Minneapolis, USA.
Christopher TignanelliCenter for Quality Outcomes, Discovery and Evaluation, University of Minnesota, Minneapolis, USA.
Stephanie MisonoCenter for Quality Outcomes, Discovery and Evaluation, University of Minnesota, Minneapolis, USA.
Jesse HoffmeisterDepartment of Otolaryngology-Head and Neck Surgery, University of Minnesota, Minneapolis, USA.ORCID 0000-0001-8891-5907

Funding

Dystonia Coalition- Pilot ProjectU54NS116025 · NINDS · EMORY UNIVERSITY · PI JINNAH, HYDER A · 2019 to 2023
$7.1M
Dystonia CoalitionU54NS065701 · NINDS · EMORY UNIVERSITY · PI JINNAH, HYDER A · 2009 to 2014
$7.0M
Dystonia CoalitionU54TR001456 · NCATS · EMORY UNIVERSITY · PI JINNAH, HYDER A · 2015 to 2016
$2.5M
Psychological factors influencing voice outcomes: Technology-based assessment and interventionK23DC016335 · NIDCD · UNIVERSITY OF MINNESOTA · PI MISONO, STEPHANIE · 2017 to 2021
$1.0M
NCATS NIH HHS U54 TR001456NIDCD NIH HHS K23 DC016335NINDS NIH HHS U54 NS065701NINDS NIH HHS U54 NS116025
6 · The paper itself

Abstract

purposePostextubation dysphagia (PED) can lead to prolonged tube feeding, but risk factors associated with prolonged tube feeding in this population are largely unknown. The purpose of this study was to identify factors independently associated with prolonged tube feeding in adult inpatients who required intubation and mechanical ventilation. MATERIALS AND

methodsRetrospective observational cohort study in a dataset of 1.3 million inpatients. Extubated adults without preventilation dysphagia or tube feeding who underwent instrumental swallowing assessment were included. To characterize factors independently associated with prolonged tube feeding, we compiled a set of potential factors, completed factor selection using a random forest algorithm, and performed logistic regression.

resultsIn total, 206 of 987 (20.9%) patients had prolonged tube feeding. The regression model produced an area under the curve of 0.79. Factors with the greatest influence on prolonged tube feeding included dysphagia with thickened liquids, dysphagia with soft/solid foods, preadmission weight loss, number of intubations, admission for neurologic disorder, and hospital of admission.

conclusionsSeveral factors predicted prolonged tube feeding after extubation. The strongest were some, but not all, aspects of swallowing function and clinical practice pattern variability. Clinical decision-making should consider bolus-specific data from instrumental swallowing evaluation rather than binary presence or absence of dysphagia.

Indexed as

Airway ExtubationDeglutition DisordersEnteral NutritionIntubation, IntratrachealRespiration, ArtificialAdultAgedDeglutitionFemaleHumansLogistic ModelsMaleMiddle AgedRetrospective StudiesRisk FactorsTime Factorsdysphagiapostextubationswallowingtube-feeding

Identifiers

PMID38850040
PMCPMC13382983

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.