Evidence map›Paper›PMID 38849886›Full record

ArticleJournal of nanobiotechnology2024

Boosting the sonodynamic performance of CoBiMn-layered double hydroxide nanoparticles via tumor microenvironment regulation for ultrasound imaging-guided sonodynamic therapy.

Shuqing Yang, Tingting Hu, Gareth R Williams, Yu Yang, Susu Zhang, Jiayi Shen, Minjiang Chen, Ruizheng Liang, Lingchun Lyu

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of nanobiotechnology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Article
  4. Review
  5. Advanced Therapeutic Approach Based on LDHs-Mimetic Oxidoreductase.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Review
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Shuqing Yang *State Key Laboratory of Chemical Resource Engineering, Beijing Advanced Innovation Center for Soft Matter Science and Engineering, Beijing University of Chemical Technology, Beijing, 100029, P. R. China.
Tingting Hu *Department Electrical and Electronic Engineering, The University of Hong Kong, Pokfulam Road, Hong Kong SAR, 999077, P. R. China.
Gareth R WilliamsUCL School of Pharmacy, University College London, 29-39 Brunswick Square, London, WC1N 1AX, UK.
Yu YangState Key Laboratory of Chemical Resource Engineering, Beijing Advanced Innovation Center for Soft Matter Science and Engineering, Beijing University of Chemical Technology, Beijing, 100029, P. R. China.
Susu ZhangLishui Central Hospital and the Fifth Affiliated Hospital of Wenzhou Medical University, Lishui, 323000, P. R. China.
Jiayi ShenLishui Central Hospital and the Fifth Affiliated Hospital of Wenzhou Medical University, Lishui, 323000, P. R. China.
Minjiang ChenLishui Central Hospital and the Fifth Affiliated Hospital of Wenzhou Medical University, Lishui, 323000, P. R. China. minjiangchen@wmu.edu.cn.
Ruizheng LiangState Key Laboratory of Chemical Resource Engineering, Beijing Advanced Innovation Center for Soft Matter Science and Engineering, Beijing University of Chemical Technology, Beijing, 100029, P. R. China. liangrz@mail.buct.edu.cn.
Lingchun LyuLishui Central Hospital and the Fifth Affiliated Hospital of Wenzhou Medical University, Lishui, 323000, P. R. China. lvlingchun@medmail.com.cn.

Funding

Fundamental Research Funds for the Central Universities of Beijing University of Chemical Technology XK1803-05National Natural Science Foundation of China 22288102National Natural Science Foundation of China-Excellent Young Scientists Fund 52322317
6 · The paper itself

Abstract

Sonodynamic therapy (SDT), a promising strategy for cancer treatment with the ability for deep tissue penetration, has received widespread attention in recent years. Sonosensitizers with intrinsic characteristics for tumor-specific curative effects, tumor microenvironment (TME) regulation and tumor diagnosis are in high demand. Herein, amorphous CoBiMn-layered double hydroxide (a-CoBiMn-LDH) nanoparticles are presented as multifunctional sonosensitizers to trigger reactive oxygen species (ROS) generation for ultrasound (US) imaging-guided SDT. Hydrothermal-synthesized CoBiMn-LDH nanoparticles are etched via a simple acid treatment to obtain a-CoBiMn-LDH nanoparticles with abundant defects. The a-CoBiMn-LDH nanoparticles give greater ROS generation upon US irradiation, reaching levels ~ 3.3 times and ~ 8.2 times those of the crystalline CoBiMn-LDH nanoparticles and commercial TiO

Indexed as

HydroxidesNanoparticlesReactive Oxygen SpeciesTumor MicroenvironmentUltrasonic TherapyAnimalsApoptosisCell Line, TumorCobaltFemaleHumansMiceMice, Inbred BALB CMice, NudeNeoplasmsUltrasonographyCobaltHydroxidesReactive Oxygen SpeciesLayered double hydroxidesSonodynamic therapySonosensitizersTumor microenvironmentUS imaging

Identifiers

PMID38849886
PMCPMC11161954

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.