Evidence map›Paper›PMID 38849878›Full record

ArticleLipids in health and disease2024

Association between monocyte-to-high-density lipoprotein-cholesterol ratio and gallstones in U.S. adults: findings from the National Health and Nutrition Examination Survey 2017-2020.

Xingwu Liu, Guanyu Yan, Boyang Xu, Mingjun Sun

Abstract read
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Article in Lipids in health and disease, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

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18citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed.

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  18. The Association of Monocytes/High-Density Lipoprotein Cholesterol Ratio With Cardiovascular-Kidney-Metabolic Syndrome and Its All-Cause Mortality - Evidence From NHANES 2003-2018.Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis
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4 · The record

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5 · Who and what money

Authors and funding

4 authors.

Xingwu LiuDepartment of Gastroenterology, The First Hospital of China Medical University, Shenyang, China.
Guanyu YanDepartment of Endoscopy, The First Hospital of China Medical University, Shenyang, China.
Boyang Xu *Department of Endoscopy, The First Hospital of China Medical University, Shenyang, China. xuboyang95@163.com.
Mingjun Sun *Department of Gastroenterology, The First Hospital of China Medical University, Shenyang, China. sunmjmw@163.com.

Funding

Major Science and Technology Project of Liaoning Province 2022JH1/10400002
6 · The paper itself

Abstract

backgroundStudies have indicated that monocyte-to-high-density lipoprotein cholesterol ratio (MHR) can be a reliable indicator of various diseases. However, the association between MHR and gallstone prevalence remains unclear. Therefore, this study aimed to explore any potential association between MHR and gallstone prevalence.

methodsThis study used data from the National Health and Nutrition Examination Survey (NHANES) 2017-March 2020. MHR was calculated as the monocyte count ratio to high-density lipoprotein cholesterol levels. Multiple logistic regression models, Cochran-Armitage trend test, and subgroup analyses were used to examine the association between MHR and gallstones.

resultsThis study included 5907 participants, of whom 636 (10.77%) were gallstone formers. The study participants had a mean age of 50.78 ± 17.33 years. After accounting for multiple covariables, the multiple logistic regression model showed a positive linear association between MHR and gallstone odds. The subgroup analyses and interaction testing results revealed that the association between MHR and gallstones was statistically different across strata, including sex, smoking, asthma, and hypertension.

conclusionsGallstone prevalence positively associated with elevated MHR, indicating that MHR can be employed as a clinical indicator to assess gallstone prevalence.

Indexed as

Cholesterol, HDLGallstonesMonocytesNutrition SurveysAdultAgedFemaleHumansLogistic ModelsMaleMiddle AgedPrevalenceRisk FactorsUnited StatesCholesterol, HDLCross-sectional studyGallstoneMonocyte-to-high-density lipoprotein-cholesterol ratioNHANES

Identifiers

PMID38849878
PMCPMC11157827

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.