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ArticleIndian journal of gastroenterology : official journal of the Indian Society of Gastroenterology2024

Sarcopenia in cirrhosis: Unraveling the prevalence and relationships with liver disease severity and complications.

Tahir Majeed, Brij Sharma, Rajesh Sharma, Vishal Bodh, Ashish Chauhan, Mukesh Surya, Bilal Ahmad Mir, Neetu Sharma, Dikshant Sharma

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Article in Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors.

Tahir MajeedDepartment of Gastroenterology and Hepatology, Indira Gandhi Medical College, Shimla, 171 001, India.
Brij SharmaDepartment of Gastroenterology and Hepatology, Indira Gandhi Medical College, Shimla, 171 001, India. drbrijsharma01@gmail.com.ORCID 0000-0001-7153-9597
Rajesh SharmaDepartment of Gastroenterology and Hepatology, Indira Gandhi Medical College, Shimla, 171 001, India.
Vishal BodhDepartment of Gastroenterology and Hepatology, Indira Gandhi Medical College, Shimla, 171 001, India.
Ashish ChauhanDepartment of Gastroenterology and Hepatology, Indira Gandhi Medical College, Shimla, 171 001, India.
Mukesh SuryaDepartment of Radio-Diagnosis and Imaging, Indira Gandhi Medical College, Shimla, 171 001, India.
Bilal Ahmad MirDepartment of Gastroenterology and Hepatology, Indira Gandhi Medical College, Shimla, 171 001, India.
Neetu SharmaDepartment of Physiology, Indira Gandhi Medical College, Shimla, 171 001, India.
Dikshant SharmaPJLN Medical College, Chamba, 175 008, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND AND

objectivesSarcopenia in cirrhosis is associated with poor survival and adverse pre and post-transplant outcomes. The study aimed at determining the prevalence of sarcopenia and its association with the severity, complications and etiology of liver disease.

methodsAs many as 416 cirrhotic patients who met the inclusion criteria underwent muscle strength testing using a dynamometer. As many as 109 probable sarcopenia patients underwent computed tomography (CT) scan to measure skeletal muscle index (SMI) at the L3 vertebral level and gait-speed testing. The gender-specific cut-offs used to define sarcopenia were an SMI of 36.54 cm

resultsThe mean age was 54.7 ± 9.51 years and male:female ratio was 2.2:1.The mean body mass index (BMI) was 24.2 ± 1.34 kg/m

conclusionThe prevalence of sarcopenia and severe sarcopenia was found to be 10.09% and 6.73%, respectively. Sarcopenia and severe sarcopenia had a significant association with the severity and complications of cirrhosis. However, no association was observed with etiology of liver disease.

Indexed as

Liver CirrhosisSarcopeniaSeverity of Illness IndexAdultAgedFemaleHumansMaleMiddle AgedMuscle StrengthPrevalenceTomography, X-Ray ComputedChild-PughCirrhosisMELD; DynamometerPrevalenceProbable sarcopeniaSarcopeniaSevere sarcopeniaSkeletal muscle areaSkeletal muscle index

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.