Evidence map›Paper›PMID 38849604›Full record

Trial reportSupportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer2024

Exploring relationships with food after dietary intervention in patients with colorectal cancer: a qualitative analysis from the Protein Recommendations to Increase Muscle (PRIMe) trial.

Katherine L Ford, Maira Quintanilha, Claire F Trottier, Wendy Wismer, Michael B Sawyer, Mario Siervo, Nicolaas E P Deutz, Helen Vallianatos, Carla M Prado

Registry-linked trialAbstract readRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02788955 (Decreasing the Burden of Sarcopenia in Cancer Through Targeted Nutrition Intervention), which is not on this map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02788955 nacompletednot on this map

Decreasing the Burden of Sarcopenia in Cancer Through Targeted Nutrition Intervention: A Feasibility Study

TypeinterventionalSponsorUniversity of AlbertaRan2016 to 2022Enrolled50ConditionsColorectal CancerArmsDietary counselling, Dietary Protein
3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Katherine L FordDepartment of Agricultural, Food & Nutritional Science, University of Alberta, 116 St and 85 Ave, Edmonton, AB, T6G 2R3, Canada.
Maira QuintanilhaDepartment of Agricultural, Food & Nutritional Science, University of Alberta, 116 St and 85 Ave, Edmonton, AB, T6G 2R3, Canada.
Claire F TrottierDepartment of Agricultural, Food & Nutritional Science, University of Alberta, 116 St and 85 Ave, Edmonton, AB, T6G 2R3, Canada.
Wendy WismerDepartment of Agricultural, Food & Nutritional Science, University of Alberta, 116 St and 85 Ave, Edmonton, AB, T6G 2R3, Canada.
Michael B SawyerDepartment of Oncology, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, Canada.
Mario SiervoSchool of Population Health, Curtin University, Perth, Australia.
Nicolaas E P DeutzCenter for Translational Research in Aging and Longevity, Texas A&M University, College Station, TX, USA.
Helen VallianatosDepartment of Anthropology, University of Alberta, Edmonton, Canada. vallianatos@ualberta.ca.
Carla M PradoDepartment of Agricultural, Food & Nutritional Science, University of Alberta, 116 St and 85 Ave, Edmonton, AB, T6G 2R3, Canada. carla.prado@ualberta.ca.

Funding

Government of Alberta Campus Alberta Innovation Program
6 · The paper itself

Abstract

purposePatients with cancer often experience nutritional challenges and are vulnerable to muscle mass loss. While substantial research is directed towards understanding how nutritional interventions affect clinical outcomes, insights into patients' personal experiences during these trials remain limited. This qualitative study aimed to gain a deeper understanding of how participation in the Protein Recommendations to Increase Muscle (PRIMe) trial affected patients' relationships with food.

methodsA subset of patients who completed a minimum of one follow-up visit in the PRIMe trial participated in a semi-structured interview about their experience implementing dietary modifications to increase protein intake. Data from 26 patients with a recent diagnosis of stage II-IV colorectal cancer (non-cachectic) were included. Interviews were audio recorded, transcribed verbatim, and qualitative content analysis was applied.

resultsMost patients were male (65.4%) with stage II or III (69.2%) colorectal cancer and were a mean age of 57 ± 10 years. Five key themes emerged to provide a deeper understanding of patients' relationship with food after the PRIMe trial: (1) new positive perspectives on nutrition and coping with a cancer diagnosis; (2) embracing a comprehensive approach to food and nutrition; (3) facilitators promoting adherence to the intervention; (4) barriers challenging adherence to the intervention; and (5) shaping future dietary intake.

conclusionThis qualitative study explored the emotional and psychological effects of a clinical nutrition trial on patients, focusing on their relationship with food. It underscored the trial's comprehensive intervention and its enduring influence on patients, extending beyond the immediate intervention phase. The role of current perspectives, motivation, and knowledge acquisition on ability to adhere to dietary changes to increase protein intake were emphasized by patients and are key considerations for both clinicians and researchers.

trial registrationClinicalTrials.gov Identifier: NCT02788955; registration posted on 2016-06-02.

Indexed as

Colorectal NeoplasmsDietary ProteinsQualitative ResearchAdaptation, PsychologicalAdultAgedFemaleHumansMaleMiddle AgedDietary ProteinsBehavioral interventionCancerNutritionQualitative

Identifiers

PMID38849604

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.