Evidence map›Paper›PMID 38849476›Full record

ArticleBritish journal of cancer2024

Anthropometric traits and risk of multiple myeloma: differences by race, sex and diagnostic clinical features.

Kevin D Arnold, Krystle L Ong, Gayathri Ravi, Hannah Cutshall, Kalyn Purnell, Meredith C Wessel, Kelly N Godby, Susan Bal, Smith Giri, Laura Q Rogers and 6 more

Abstract read
In one paragraph

Article in British journal of cancer, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Risk factors for multiple myeloma and its precursor diseases.Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences · 2025
    Review
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Kevin D ArnoldDepartment of Pathology, Heersink School of Medicine, University of Alabama at Birmingham, Birmingham, AL, 35294, USA.ORCID http://orcid.org/0009-0006-1730-9700
Krystle L OngDepartment of Pathology, Heersink School of Medicine, University of Alabama at Birmingham, Birmingham, AL, 35294, USA.ORCID http://orcid.org/0000-0003-0207-4006
Gayathri RaviDivision of Hematology and Medical Oncology, Department of Medicine, Heersink School of Medicine, University of Alabama at Birmingham, Birmingham, AL, 35294, USA.
Hannah CutshallDepartment of Pathology, University of Arkansas for Medical Sciences, Little Rock, AR, 72205, USA.
Kalyn PurnellDepartment of Pathology, Heersink School of Medicine, University of Alabama at Birmingham, Birmingham, AL, 35294, USA.
Meredith C WesselDepartment of Pathology, Heersink School of Medicine, University of Alabama at Birmingham, Birmingham, AL, 35294, USA.
Kelly N GodbyDivision of Hematology and Medical Oncology, Department of Medicine, Heersink School of Medicine, University of Alabama at Birmingham, Birmingham, AL, 35294, USA.
Susan BalDivision of Hematology and Medical Oncology, Department of Medicine, Heersink School of Medicine, University of Alabama at Birmingham, Birmingham, AL, 35294, USA.
Smith GiriDivision of Hematology and Medical Oncology, Department of Medicine, Heersink School of Medicine, University of Alabama at Birmingham, Birmingham, AL, 35294, USA.
Laura Q RogersO'Neal Comprehensive Cancer Center, University of Alabama at Birmingham, Birmingham, AL, 35294, USA.
Wendy Demark-WahnefriedO'Neal Comprehensive Cancer Center, University of Alabama at Birmingham, Birmingham, AL, 35294, USA.
Faith E DaviesPerlmutter Comprehensive Cancer Center, Langone Medical Center, New York University, New York, NY, 10021, USA.
Luciano J CostaDivision of Hematology and Medical Oncology, Department of Medicine, Heersink School of Medicine, University of Alabama at Birmingham, Birmingham, AL, 35294, USA.
Gareth J MorganPerlmutter Comprehensive Cancer Center, Langone Medical Center, New York University, New York, NY, 10021, USA.
Brenda M BirmannChanning Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, 02115, USA.ORCID http://orcid.org/0000-0002-7550-5498
Elizabeth E BrownDepartment of Pathology, Heersink School of Medicine, University of Alabama at Birmingham, Birmingham, AL, 35294, USA. elizabethbrown@uabmc.edu.ORCID http://orcid.org/0000-0003-4498-7858

Funding

XRAY CRYSTALLOGRAPHYP30CA013148 · NCI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI Robert S Welner · 1985 to 2026
$165.9M
TRAINING AND CAREER DEVELOPMENTU54CA118948 · NCI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI UPENDER MANNE · 2005 to 2026
$26.6M
IMMUNOLOGIC DISEASES AND BASIC IMMUNOLOGYT32AI007051 · NIAID · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI Laurie Ellen Harrington · 1985 to 2026
$13.1M
Epigenetic contribution to the excess risk of MGUS in African AmericansU01CA249955 · NCI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI BROWN, ELIZABETH E · 2021 to 2025
$3.0M
Molecular characterization of myeloma and related asymptomatic precursor statesR01CA186646 · NCI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI BROWN, ELIZABETH E, VACHON, CELINE M · 2014 to 2018
$3.0M
A genome-wide methylation study of epigenetic contributions to multiple myelomaR21CA155951 · NCI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI BROWN, ELIZABETH E · 2011 to 2012
$347k
The Role of Exosome Heparanase and miRNAs as Biomarkers for MyelomaR21CA182861 · NCI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI BROWN, ELIZABETH E, SANDERSON, RALPH D · 2014 to 2015
$261k
American Cancer Society (American Cancer Society, Inc.) IRG60-001-47NCI NIH HHS P30 CA013148NCI NIH HHS R01 CA186646NCI NIH HHS R21 CA155951NCI NIH HHS R21 CA182861NCI NIH HHS U01 CA249955NCI NIH HHS U54 CA118948NIAID NIH HHS T32 AI007051
6 · The paper itself

Abstract

backgroundObesity is an established modifiable risk factor for multiple myeloma (MM). However, associations of obesity and MM risk in Black populations, for whom obesity and MM are more common, is less clear.

methodsUsing participants enrolled in the Integrative Molecular And Genetic Epidemiology study, we evaluated the association of anthropometric traits with MM risk overall, stratified by race and sex. Among cases, we assessed the association of BMI with the presence of myeloma-defining events.

resultsWe observed an 18% increase in MM risk for every 5 kg/m

conclusionsFindings underscore the importance of obesity as a modifiable risk factor for MM, particularly in high-risk populations, and for the clinical presentation of disease.

Indexed as

Body Mass IndexMultiple MyelomaObesityAdultAgedAnthropometryBlack or African AmericanFemaleHumansMaleMiddle AgedRisk FactorsSex FactorsWhite

Identifiers

PMID38849476
PMCPMC11263363

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.