Evidence map›Paper›PMID 38849466›Full record

ArticleScientific reports2024

Oxidative modification of miR-30c promotes cardiac fibroblast proliferation via CDKN2C mismatch.

Wenguang Chang, Dandan Xiao, Xinyu Fang, Jianxun Wang

Abstract read
In one paragraph

Article in Scientific reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Review
  2. Review
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  4. Review
  5. Review
  6. Epigenetic Mechanisms in Heart Diseases.Reviews in cardiovascular medicine · 2025
    Review
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Wenguang ChangSchool of Basic Medical Sciences, College of Medicine, Qingdao University, Qingdao, China.
Dandan XiaoSchool of Basic Medical Sciences, College of Medicine, Qingdao University, Qingdao, China.
Xinyu FangSchool of Basic Medical Sciences, College of Medicine, Qingdao University, Qingdao, China.
Jianxun WangSchool of Basic Medical Sciences, College of Medicine, Qingdao University, Qingdao, China. wangsubmit@126.com.

Funding

National Natural Science Foundation of China 81770232
6 · The paper itself

Abstract

The response of cardiac fibroblast proliferation to detrimental stimuli is one of the main pathological factors causing heart remodeling. Reactive oxygen species (ROS) mediate the proliferation of cardiac fibroblasts. However, the exact molecular mechanism remains unclear. In vivo, we examined the oxidative modification of miRNAs with miRNA immunoprecipitation with O

Indexed as

Cell ProliferationFibroblastsMicroRNAsOxidation-ReductionAngiotensin IIAnimalsFibrosisMaleMiceMyocardiumRatsReactive Oxygen SpeciesAngiotensin IIMicroRNAsMIRN30 microRNA, ratReactive Oxygen SpeciesCardiac fibrosisCDKN2CmiR-30cO8GOxidation modification

Identifiers

PMID38849466
PMCPMC11161483

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.