Evidence map›Paper›PMID 38848540›Full record

ReviewNano letters2024

Biomimetic Ghost Nanomedicine-Based Optotheranostics for Cancer.

Rajendra Prasad, Vaskuri G S Jyothi, Nagavendra Kommineni, Ravi Teja Bulusu, Bárbara B Mendes, Jonathan F Lovell, João Conde

Abstract readReview
In one paragraph

Review in Nano letters, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Long-Term Cell-Membrane-Coated Ultrabright Nanospheres for Targeted Cancer Cell Imaging and Hydrophobic Drug Delivery.Chemistry of materials : a publication of the American Chemical Society · 2025
    Article
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Rajendra PrasadSchool of Biochemical Engineering, Indian Institute of Technology (BHU), Varanasi, Uttar Pradesh 221005, India.
Vaskuri G S JyothiDepartment of Pharmaceutical Sciences, University of Tennessee Health Science Center (UTHSC), Memphis, Tennessee 38163, United States.
Nagavendra KommineniCenter for Biomedical Research, Population Council, New York, New York 10065, United States.
Ravi Teja BulusuDepartment of Pharmaceutical Sciences, Florida A&M University, Tallahassee, Florida 32307, United States.
Bárbara B MendesNOVA Medical School|Faculdade de Ciências Médicas, NMS|FCM, Universidade NOVA de Lisboa, Lisbon 1169-056, Portugal.ORCID 0000-0001-8630-1119
Jonathan F LovellDepartment of Biomedical Engineering, University at Buffalo, State University of New York, Buffalo, New York 14260, United States.ORCID 0000-0002-9052-884X
João CondeNOVA Medical School|Faculdade de Ciências Médicas, NMS|FCM, Universidade NOVA de Lisboa, Lisbon 1169-056, Portugal.ORCID 0000-0001-8422-6792

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Theranostic medicine combines diagnostics and therapeutics, focusing on solid tumors at minimal doses. Optically activated photosensitizers are significant examples owing to their photophysical and chemical properties. Several optotheranostics have been tested that convert light to imaging signals, therapeutic radicals, and heat. Upon light exposure, conjugated photosensitizers kill tumor cells by producing reactive oxygen species and heat or by releasing cancer antigens. Despite clinical trials, these molecularly conjugated photosensitizers require protection from their surroundings and a localized direction for site-specific delivery during blood circulation. Therefore, cell membrane biomimetic ghosts have been proposed for precise and safe delivery of these optically active large molecules, which are clinically relevant because of their biocompatibility, long circulation time, bypass of immune cell recognition, and targeting ability. This review focuses on the role of biomimetic nanoparticles in the treatment and diagnosis of tumors through light-mediated diagnostics and therapy, providing insights into their preclinical and clinical status.

Indexed as

Biomimetic MaterialsNeoplasmsPhotosensitizing AgentsTheranostic NanomedicineAnimalsBiomimeticsHumansNanomedicineNanoparticlesPhotosensitizing AgentsBiomimeticsCell GhostsOptotheranosticsPhototherapeuticsSolid tumors

Identifiers

PMID38848540
PMCPMC11247544

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.