Evidence map›Paper›PMID 38848363›Full record

ArticleScience advances2024

Multiplexed CRISPR-Cas9 mutagenesis of rice

Dhruv Patel-Tupper, Armen Kelikian, Anna Leipertz, Nina Maryn, Michelle Tjahjadi, Nicholas G Karavolias, Myeong-Je Cho, Krishna K Niyogi

Abstract read
In one paragraph

Article in Science advances, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed.

  1. Review
  2. A NovelPlants (Basel, Switzerland) · 2026
    Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Review
  9. Review
  10. Review
  11. Article
  12. CRISPR-Cas applications in agriculture and plant research.Nature reviews. Molecular cell biology · 2025
    Review
  13. Needs and opportunities to future-proof crops and the use of crop systems to mitigate atmospheric change.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2025
    Review
  14. Impact of climate-driven changes in temperature on stomatal anatomy and physiology.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2025
    Review
  15. Review
  16. Review
  17. Article
  18. Chlorophyll to zeaxanthin energy transfer in nonphotochemical quenching: An exciton annihilation-free transient absorption study.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  19. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors.

Dhruv Patel-TupperDepartment of Plant and Microbial Biology, University of California, Berkeley, CA 94720, USA.ORCID 0000-0002-0642-1485
Armen KelikianDepartment of Plant and Microbial Biology, University of California, Berkeley, CA 94720, USA.ORCID 0009-0009-6021-8822
Anna LeipertzDepartment of Plant and Microbial Biology, University of California, Berkeley, CA 94720, USA.
Nina MarynDepartment of Plant and Microbial Biology, University of California, Berkeley, CA 94720, USA.ORCID 0000-0002-0975-3354
Michelle TjahjadiInnovative Genomics Institute, University of California, Berkeley, CA 94720, USA.
Nicholas G KaravoliasDepartment of Plant and Microbial Biology, University of California, Berkeley, CA 94720, USA.
Myeong-Je ChoInnovative Genomics Institute, University of California, Berkeley, CA 94720, USA.ORCID 0000-0002-7638-7235
Krishna K NiyogiDepartment of Plant and Microbial Biology, University of California, Berkeley, CA 94720, USA.ORCID 0000-0001-7229-2071

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Understanding CRISPR-Cas9's capacity to produce native overexpression (OX) alleles would accelerate agronomic gains achievable by gene editing. To generate OX alleles with increased RNA and protein abundance, we leveraged multiplexed CRISPR-Cas9 mutagenesis of noncoding sequences upstream of the rice

Indexed as

CRISPR-Cas SystemsGene EditingMutagenesisOryzaAllelesGene Expression Regulation, PlantPlant ProteinsPlants, Genetically ModifiedTransgenesPlant Proteins

Identifiers

PMID38848363
PMCPMC11160471

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.